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Table 1 Biology changes through hospitalization

From: Severe COVID-19 with acute respiratory distress syndrome (ARDS) in a sickle cell disease adult patient: case report

Day from admission

D0

D1

D5

D15

D27

D34

Variables

Normal range

ED admission

ICU admission

ECMO initiation

ECMO explantation

ICU discharge

Hospital discharge

Blood count

Hemoglobin (g/dL)

12.0–18.0

11.5

10.7

10.6

8.8

10.14

7.2

Reticulocytes count (× 10.9/L)

25–125

48

38

71

361

367

331

White blood cell count (× 10.9/L)

4.0–10.0

10.5

13.86

43.29

16.37

10.14

14.79

Neutrophils (× 10.9/L)

1.7–7.0

9.44

12.29

31.64

11.63

5.57

9.73

Lymphocytes (× 10.9/L)

1.5–4.0

0.71

0.98

3.18

2.56

3,17

3.03

Platelets (× 10.9/L)

150–400

171

182

203

195

367.2

228

Inflam

C reactive protein mg/L

 < 5.0

300.9

343.6

303.7

160.1

63.3

20.2

Procalcitonin µg/L

 < 0.5

 

1.78

1.56

0.38

0.59

 

Hemostasis

PT (%)

 > 70

 

75

78

83

71

 

Fibrinogen (g/L)

1.80–4.0

 

9.4

7.8

6.4

6.0

 

D-dimers (ng/mL)

 < 500

 

3030

947

 > 20,000

2379

 

Hemolysis

ASAT (IU/L)

 < 35

 

27

464

64

55

 

ALAT (IU/L)

 < 43

 

9

235

47

39

 

Serum lactate dehydrogenase (IU/L)

125–250

393

438

2498

1044

709

 

Total bilirubin (µmol/L)

 < 17

 

24

20

 

25