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Table 2 Microorganisms identified in early-onset VAP (n = 42) and late-onset VAP (n = 148)

From: Microorganisms and clinical outcomes of early- and late-onset ventilator-associated pneumonia at Srinagarind Hospital, a tertiary center in Northeastern Thailand

Microorganism

Early-onset VAP

n (%)

Late-onset VAP

n (%)

p-value

Gram-negative organism

40 (95.2)

145 (97.9)

0.31

 Acinetobacter baumannii

21 (50.0)

78 (52.7)

0.76

  MDR Acinetobacter baumannii

20 (47.6%)

73 (49.3)

0.84

 Klebsiella pneumoniae

8 (19.0)

21 (14.2)

0.44

  MDR Klebsiella pneumoniae

1 (2.4)

18 (12.2)

 

  ESBL-Klebsiella pneumoniae

0 (0.0)

5 (3.4)

 

  CRE Klebsiella pneumoniae

1 (2.4)

9 (6.1)

 

 Pseudomonas aeruginosa

3 (7.1)

14 (9.5)

0.64

  MDR Pseudomonas aeruginosa

1 (2.4)

2 (1.4)

 

 Stenotrophomonas maltophilia

2 (4.8)

23 (15.5)

0.07

  MDR Stenotrophomonas maltophilia

2 (4.8)

22 (14.9)

 

 Enterobacter spp.

2 (4.8)

2 (1.4)

0.17

  MDR Enterobacter spp.

1 (2.4)

2 (1.4)

 

  ESBL-Enterobacter spp.

1 (2.4)

1 (2.4)

 

 Other gram-negative organisms

4 (1.7)

7 (4.73)

 

Gram-positive organism

2 (4.8)

3 (2.0)

0.24

Staphylococcus aureus

1 (2.4)

2 (1.4)

0.31

  MRSA

1 (2.4)

2 (1.4)

0.64

 Other gram-positive organisms

1 (2.4)

1 (0.7)

0.33

Multidrug-resistant pathogens**

26 (61.9)

121 (81.8)

0.007*

  1. VAP ventilator-associated pneumonia, ESBL extended-spectrum beta-lactamase, CRE carbapenem-resistant Enterobacteriaceae, MRSA methicillin-resistant Staphylococcus aureus
  2. *p-value < 0.05
  3. **Multidrug-resistant pathogens included ESBLs, CRE, MRSA, and other MDR organisms