Table 1 Baseline characteristics, pre-challenge spirometry and sputum cells of patients with CVA and CA

n

263

351

–

Age, years

46.06 ± 16.43

48.64 ± 15.85

0.051

Females, n (%)

164, (62.36%)

190, (54.13%)

0.041

BMI, kg/m²

23.54 ± 3.62

23.50 ± 3.56

0.902

Smokers, n (%)

56, (21.29%)

95, (27.07%)

0.100

FVC% predicted

97.55 (13.48)

96.47 (12.92)

0.317

FEV₁ (L)

2.41 (0.65)

2.29 (0.63)

0.023

FEV₁% predicted

89.21 (11.84)

85.02 (12.36)

< 0.001

FEV₁/FVC (%)

76.46 (8.62)

73.12 (9.77)

< 0.001

PEF% predicted

89.89 (15.15)

87.10 (16.75)

0.028

MMEF% predicted (< 65%), n (%)

184 (70%)

284 (80.91%)

0.002

FEF_50% predicted (< 65%), n (%)

165 (62.74%)

258 (73.5%)

0.004

FEF_75% predicted (< 65%), n (%)

199 (75.67%)

277 (78.92%)

0.379

MMEF% predicted

56.10 (18.26)

49.52 (19.57)

< 0.001

FEF_50% predicted

60.54 (19.46)

52.76 (20.16)

< 0.001

FEF_75% predicted

53.37 (20.18)

47.10 (22.92)

< 0.001

PD₂₀ (mcg)

0.89 (0.79)

0.71 (0.8)

0.005

FEV₁ fall (%)

26.95 (7.92)

29.65 (11.48)

0.001

n

241

218

–

Sputum eosinophils, %

9.32 ± 14.37

13.57 ± 19.76

0.009

Sputum neutrophils, %

74.56 ± 20.45

69.25 ± 22.89

0.008