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Table 2 Predictors for intubation in derivation and full cohorts

From: A scoring system derived from electronic health records to identify patients at high risk for noninvasive ventilation failure

Factor

Derivation cohort

Full cohort

Odds ratio (95% CI)

Odds ratio (95% CI)

Points

Number of organs failed

   

None

Referent

Referent

 

One

2.29 (2.08, 2.53)

2.37 (2.19, 2.56)

4

Two or more

5.46 (4.95, 6.02)

5.34 (4.94, 5.78)

8

Primary diagnostic group

   

Acute myocardial infarct

Referent

Referent

 

COPD/asthma

3.24 (2.77, 3.80)

2.94 (2.59, 3.34)

5

Congestive heart failure

1.80 (1.49, 2.17)

1.52 (1.30, 1.78)

2

Pneumonia or Sepsis

3.94 (3.40, 4.56)

3.54 (3.15, 3.98)

6

Neuro non-stroke

5.53 (4.55, 6.72)

5.35 (4.56, 6.32)

8

Stroke

6.84 (5.62, 8.33)

6.18 (5.28, 7.24)

8

Substance abuse or psychosis

10.09 (8.47, 12.01)

8.70 (7.58, 9.99)

10

Other

1.78 (1.49, 2.14)

1.54 (1.33, 1.77)

2

Pneumonia (secondary dgn)

2.27 (2.04, 2.53)

2.21 (2.02, 2.42)

4

Prior year invasive mechanical vent

2.98 (2.51, 3.53)

3.05 (2.65, 3.51)

5

Systolic blood pressure

   

 ≥ 91

Referent

Referent

 

 ≤ 90

1.55 (1.42, 1.68)

1.51 (1.42, 1.62)

2

Body mass index

   

18.0—25.0

Referent

Referent

 

 < 18.5

1.18 (1.02, 1.36)

1.23 (1.10, 1.39)

1

Bicarbonate

   

22 – 27

Referent

Referent

 

 < 22

0.96 (0.88, 1.04)

1.02 (0.96, 1.10)

1

Weight loss (secondary dgn)

1.51 (1.35, 1.68)

1.48 (1.35, 1.62)

2

No prior year admissions

1.42 (1.31, 1.55)

1.41 (1.32, 1.51)

2

Respiratory rate

   

 ≤ 29

Referent

Referent

 

 ≥ 30

1.75 (1.33, 2.30)

1.92 (1.53, 2.40)

3

  1. For physiological variables we chose the worst value in the 24 h prior to NIV initiation