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Table 1 Pathophysiological causes of diaphragmatic dysfunction

From: Ultrasound and non-ultrasound imaging techniques in the assessment of diaphragmatic dysfunction

Group

Examples

Neuronal disorders

 

a) Disorders of CNS

Poliomyelitis, ALS, multiple sclerosis, spinal cord injury

b) Disorders of peripheral neurons

Guillain–Barre syndrome, chronic inflammatory demyelinating polyneuropathy, critical illness polyneuropathy, compression of the phrenic nerve by neighboring structures

Disorders of the neuromuscular junction

Myasthenia gravis, Lambert-Eaton syndrome, botulism, organophosphates

Disorders of the muscle 

Muscular dystrophies, critical-illness myopathy, acid maltase deficiency (Pompe disease), dermatomyositis

  1. CNS central nervous system, ALS amyotrophic lateral sclerosis