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Table 3 Univariate and multivariate analysis of disease-free-survival (DFS)

From: Prognostic value of the preoperative lymphocyte-to-monocyte ratio for survival after lung cancer surgery

Covariables

Hazard ratio

95% CI

p value

Univariate analysis

PLR ≥ 150

0.986

0.654–1.488

0.948

NLR ≥ 2.5

1.203

0.821–1.761

0.343

LMR ≥ 2.5

0.444

0.289–0.683

0.001

Age

1.018

0.996–1.040

0.112

Sex (female)

0.970

0.595–1.579

0.901

Pathological stage

0.051*

 I

1.000

  

 II

1.686

1.126–2.526

0.011

 III

1.793

0.812–3.958

0.148

 IV

2.536

0.350–18.380

0.357

Histological type

0.219*

 Adenocarcinoma

1.000

  

 Squamous cell carcinoma

0.618

0.384–0.995

0.048

 Large cell carcinoma

0.792

0.381–1.646

0.532

 Other

0.568

0.138–2.343

0.434

Multivariate analysis

LMR ≥ 2.5

0.476

0.307–0.738

0.001

Age

1.029

1.005–1.054

0.017

Sex

 Male

1.000

  

 Female

1.171

0.693–1.977

0.556

Pathological stage

0.027*

 I

1.000

  

 II

1.779

1.174–2.695

0.007

 III

1.878

0.848–4.162

0.120

 IV

3.101

0.406–23.695

0.275

Histological type

0.053*

 Adenocarcinoma

1.000

  

 Squamous cell carcinoma

0.527

0.322–0.862

0.011

 Large cell carcinoma

0.619

0.294–1.301

0.205

 Other

0.541

0.127–2.306

0.407

  1. LMR lymphocyte-to-monocyte ratio, NLR neutrophil-to-lymphocyte ratio, PLR platelet-to-lymphocyte ratio
  2. *Linear trend p value