Fig. 2
From: Detection of EGFR mutation of pulmonary adenocarcinoma in sputum using droplet digital PCR
Cytological findings of sputum and histological findings of resected specimen in Case 1 to 3 of the 13 SC (+) cases. a–c Case 1 was diagnosed with invasive papillary adenocarcinoma with pT3N2M0 stage IIIA. a The sputum cytology revealed adenocarcinoma (class V). b, c STAS with solid nests or single cells features was detected in FFPE sections of the surgically resected tumors. d–f Case 2 was diagnosed with invasive lepidic adenocarcinoma with pT1cN1M0 stage IIB. d Adenocarcinoma was suspected (class IIIb) in the sputum cytology. e, f STAS with micropapillary feature was detected in FFPE sections of the surgically resected tumors. g, h Case 3 was diagnosed with invasive mucinous adenocarcinoma with pT3N2M0 stage IIIA. g The sputum cytology revealed adenocarcinoma (class V). h STAS with solid nests feature was detected in FFPE sections of the surgically resected tumors