Table 2 Sensitivity, specificity, and positive predictive value of EGFR mutation (Ex19 and Ex21) detection in sputum cytology positive and negative cases
From: Detection of EGFR mutation of pulmonary adenocarcinoma in sputum using droplet digital PCR
Sputum cytology positive cases | EGFR mutation (+) in surgical resected specimen | EGFR mutation (−) in surgical resected specimen | Total |
|---|---|---|---|
EGFR mutation (+) in sputum sample | 4 | 0 | 4 |
EGFR mutation (−) in sputum sample | 1 | 8 | 9 |
Total | 5 | 8 | 13 |
Sensitivity = 80.0% Specificity = 100% Positive predictive value = 100% |  |  |  |
Sputum cytology negative cases | EGFR mutation (+) in surgical resected specimen | EGFR mutation (−) in surgical resected specimen | Total |
|---|---|---|---|
EGFR mutation (+) in sputum sample | 1 | 0 | 1 |
EGFR mutation (−) in sputum sample | 31 | 44 | 75 |
Total | 32 | 44 | 76 |
Sensitivity = 3.1% Specificity = 100% Positive predictive value= 100% |  |  |  |