Table 4 ROC curve analysis of serum Smad4 distinguishing lung cancer
Criterion | Sensitivity | 95% CI | Specificity | 95% CI | + LR | -LR |
|---|---|---|---|---|---|---|
Calculation of critical value of serum Smad4 in lung cancer and healthy people | ||||||
> 35 | 100.00 | 96.7–100.0 | 13.64 | 7.8–21.5 | 1.16 | 0.00 |
> 46.6 | 99.09 | 95.0–100.0 | 20.91 | 13.7–29.7 | 1.25 | 0.043 |
> 47 | 97.27 | 92.2–99.4 | 21.82 | 14.5–30.7 | 1.24 | 0.12 |
> 97 | 97.27 | 92.2–99.4 | 51.82 | 42.1–61.4 | 2.02 | 0.053 |
> 98 | 96.36 | 91.0–99.0 | 53.64 | 43.9–63.2 | 2.08 | 0.068 |
> 104* | 91.56 | 81.0–99.0 | 69.16 | 50.2–69.2 | 2.41 | 0.061 |
> 123.4 | 73.64 | 64.4–81.6 | 72.36 | 56.7–78.1 | 2.19 | 0.40 |
> 147.8 | 25.45 | 17.6–34.6 | 79.73 | 63.4–85.8 | 0.93 | 1.02 |
> 183.4 | 21.82 | 14.5–30.7 | 83.64 | 75.4–90.0 | 1.33 | 0.93 |
> 239.8 | 3.64 | 1.0–9.0 | 92.73 | 86.2–96.8 | 0.50 | 1.04 |
> 279.33 | 0.91 | 0.02–5.0 | 100.00 | 96.7–100.0 | 0.99 | |
Calculation of the critical value of serum Smad4 in lung cancer and benign lung diseases | ||||||
> 35 | 100.00 | 96.7–100.0 | 13.64 | 7.8–21.5 | 1.16 | 0.00 |
> 56 | 94.55 | 88.5–98.0 | 23.64 | 16.1–32.7 | 1.24 | 0.23 |
> 65 | 94.55 | 88.5–98.0 | 35.45 | 26.6–45.1 | 1.46 | 0.15 |
> 86 | 88.18 | 80.6–93.6 | 50.91 | 41.2–60.6 | 1.80 | 0.23 |
> 122* | 84.55 | 76.4–90.7 | 60.36 | 56.7–75.1 | 2.51 | 0.23 |
> 127 | 83.64 | 75.4–90.0 | 62.18 | 58.6–76.7 | 2.63 | 0.24 |
> 136 | 58.18 | 48.4–67.5 | 71.82 | 62.4–80.0 | 2.06 | 0.58 |
> 147 | 33.64 | 24.9–43.3 | 75.45 | 66.3–83.2 | 1.37 | 0.88 |
> 201 | 26.36 | 18.4–35.6 | 92.73 | 86.2–96.8 | 3.62 | 0.79 |
> 273 | 7.27 | 3.2–13.8 | 99.09 | 95.0–100.0 | 8.00 | 0.94 |
> 297.4 | 3.64 | 1.0–9.0 | 100.00 | 96.7–100.0 | 0.96 | |