Table 6 Expression of Smad4 in lung cancer tissues (N = 52)
Parameter | Group | N | Expression of Smad4 | |||
|---|---|---|---|---|---|---|
Negative (%) | Positive (%) | χ2 value | P value | |||
Specimen source | Normal | 52 | 14 (26.9) | 38 (73.1) | 5.798 | 0.009 |
Cancerous | 52 | 27 (51.9) | 25 (48.1) | |||
Gender | Male | 31 | 15 (48.4) | 16 (51.6) | 0.384 | 0.535 |
Female | 21 | 12 (57.1) | 9 (42.9) | |||
Ages | < 60 | 29 | 15 (51.7) | 14 (48.3) | 0.001 | 0.974 |
≥ 60 | 23 | 12 (52.2) | 11 (47.8) | |||
Smoking | No | 27 | 13 (48.1) | 14 (51.9) | 0.321 | 0.571 |
Yes | 25 | 14 (56) | 11 (44) | |||
Histology | LAC | 19 | 12 (63.2) | 7 (36.8) | 1.514 | 0.219 |
LSCC | 33 | 15 (45.5) | 18 (54.5) | |||
Pathological grade | Poorly | 11 | 10 (90.9) | 1 (9.1) | 10.264 | 0.006 |
Moderately | 19 | 10 (52.6) | 9 (47.4) | |||
Well | 22 | 7 (31.8) | 15 (68.2)* | |||
Lymph node metastasis | N0–N1 | 37 | 15 (40.5) | 22 (59.5) | 6.657 | 0.010 |
N2–N3 | 15 | 12 (80) | 3 (20) | |||
TNM | IB-IIB | 29 | 8 (27.6) | 21 (72.4) | 15.55 | < 0.001 |
IIIA | 23 | 19 (82.6) | 4 (17.4) | |||