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Table 2 Comparing outcomes within and between two study group

From: The effect of atorvastatin on inflammatory markers in sulfur mustard gas induced bronchitis: a randomized double-blinded, placebo-control clinical trial

 

Atorvastatin group

(n = 40)

Placebo group

(n = 38)

Difference between groups after 12 weeks

 

Baseline

12 weeks

Mean difference (95% CI)

Effect size (95% CI)

Baseline

12 weeks

Mean difference (95% CI)

Effect size (95% CI)

Mean difference (95% CI)

Effect size (95% CI)

p value

WBC (× 103 cells/ml)

7.6 ± 2.5

7.4 ± 1.8

0.01 (− 0.6, 0.63)

0.007 (− 0.42, 0.43)

6.7 ± 1.7

6.7 ± 1.5

− 0.01 (− 0.45, 0.41)

− 0.01 (− 0.35, 0.33)

− 0.03 (− 0.8, 0.7)

0.01 (− 0.42, 0.46)

0.93

IL-6 (pg/ml)

0.92 ± 0.87

0.69 ± 0.7

0.2 (− 0.05, 0.5)

0.15 (− 0.15, 0.46)

1.1 ± 1.3

0.46 ± 0.3

0.6 (0.2, 1.05)

0.64 (0.43, 0.86)

0.4 (− 0.09, 0.9)

− 0.36 (− 0.81, 0.08)

0.07

TNF-α (pg/ml)

2.1 ± 0.4

2.2 ± 0.3

− 0.07 (− 0.2, 0.07)

− 0.19 (− 0.27, − 0.11)

1.9 ± 0.3

2.2 ± 0.4

− 0.2 (− 0.34, − 0.06)

− 0.55 (− 0.63, − 0.47)

− 0.13 (− 0.3, 0.07)

0.29 (− 0.15, 0.74)

0.20

HsCRP (ng/ml)

5.35 ± 3.2

5.49 ± 3.4

− 0.1 (− 1.2, 0.9)

− 0.04 (− 0.76, 0.67)

4.10 ± 2.9

4.45 ± 3.2

− 0.3 (− 1.4, 0.8)

− 0.11 (− 0.78, 0.55)

− 0.2 (− 1.7, 1.3)

0.06 (− 0.38, 0.5)

0.78

Procalcitonin (pg/ml)

0.043 ± 0.18

0.04 ± 0.15

0.003 (− 0.02, 0.03)

0.01 (− 0.02, 0.05)

0.038 ± 0.07

0.02 ± 0.05

0.02 (− 0.001, 0.04)

0.3 (0.29, 0.32)

0.02 (− 0.01, 0.05)

− 0.22 (− 0.67, 0.21)

0.15

CAT score

29.4 ± 7

22 ± 5.6

7.8 (5.3, 10.3)

1.3 (− .005, 2.6)

28.1 ± 6

19.6 ± 7.2

8.4 (6.4, 10.4)

1.25 (− 0.26, 2.78)

0.57 (− 2.5, 3.7)

− 0.09 (− 0.53, 0.35

0.71

Cholestrol (mg/dl)

206 ± 42

160 ± 44

42 (29, 55)

1.03 (− 8.6, 10.6)

211 ± 85

180 ± 31

18 (9.3, 27)

0.56 (− 7, 8.1)

− 24 (− 39.5, − 8.7)

0.7 (0.24, 1.15)

0.003

Low-density lipoprotein (mg/dl)

124 ± 33

100 ± 37

22 (10, 33)

0.61 (− 6.8, 8.1)

119 ± 30

116 ± 24

3.6 (− 4.2, 11.5)

0.11 (− 5.7, 6.01)

− 18 (− 31.6, − 4.7)

0.58 (0.13, 1.04)

0.009