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Table 1 Characteristics of patients with and without pneumococcal pneumonia

From: Effectiveness of a 23-valent pneumococcal polysaccharide vaccine for the prevention of pneumococcal pneumonia in the elderly with chronic respiratory diseases: a case–control study of a single center

Variable and category (reference)

Case group

(n = 164)

Control group

(n = 4,054)

p value

Age, yearsa

76.2 ± 7.3

75.1 ± 6.7

0.127

 65–69

32 (19.5)

984 (24.3)

0.153

 70–74

44 (26.8)

1,098 (27.1)

 75–79

36 (22.0)

950 (23.4)

 80 + 

56 (34.1)

1,063 (26.2)

Male (vs. female)

113 (68.9)

2,525 (62.3)

0.100

Smoking

  

0.001

 Non-smokers

37 (22.6)

1,198 (29.6)

 Current smokers

108 (65.9)

2,068 (51.0)

 Ex-smokers

19 (11.6)

788 (19.4)

Chronic respiratory diseases (vs. absent)

   

 Asthma

30 (18.3)

685 (16.9)

0.671

 COPD

42 (25.6)

959 (23.6)

0.574

 Lung cancer

45 (27.4)

1,594 (39.3)

0.002

 Interstitial pneumonia

29 (17.7)

703 (17.3)

0.916

 NTM

10 (6.1)

449 (11.1)

0.054

 Othersb

48 (29.3)

746 (18.4)

0.001

Diabetes (vs. absent)

65 (39.6)

1,209 (29.8)

0.023

Chronic heart disease (vs. absent)

95 (57.9)

1,891 (46.6)

0.005

Chronic kidney disease (vs. absent)

13 (7.9)

299 (7.4)

0.761

Systemic corticosteroid user (vs. absent)

65 (39.6)

1,189 (29.3)

0.007

  1. Values are expressed as numbers and proportions in parentheses
  2. aMean ± SD
  3. bOther chronic respiratory diseases included chronic pulmonary aspergillosis, old pulmonary tuberculosis, sarcoidosis, and chronic cough
  4. COPD, chronic obstructive pulmonary disease; NTM, non-tuberculous mycobacteriosis