Table 1 Characteristics of the patients included in the study who had TBLCs for the work-up of ILD
From: Trans-bronchial lung cryobiopsy in patients at high-risk of complications
All (n = 96) | Low-Risk (n = 58) | High-Risk (n = 38) | p value | ||
|---|---|---|---|---|---|
Patient characteristics | |||||
Gender | Male, n (%) | 53 (55) | 30 (52) | 23 (61) | 0.396 |
Age, years | Mean (SD) | 63 (9) | 62 (9) | 65 (10) | 0.165 |
Smoking history | Current, n (%) | 12 (13) | 10 (17) | 2 (5) | 0.083 |
Former, n (%) | 50 (52) | 26 (45) | 24 (63) | 0.079 | |
Never, n (%) | 34 (35) | 22 (38) | 12 (32) | 0.524 | |
BMI | Mean (SD) | 28 (5) | 27 (4) | 31 (6) | < 0.001 |
FVC, % predicted value | Mean (SD) | 72 (22) | 79 (19) | 61 (23) | < 0.001 |
DLCO, % predicted value | Mean (SD) | 51 (16) | 54 (15) | 45 (16) | 0.006 |
sPAP | Mean (SD) | 30 (9) | 27 (6) | 33 (12) | 0.005 |
Thin-section CT pattern | |||||
UIP | n (%) | 1 (1) | 1 (2) | 0 (0) | 0.419 |
Probable UIP | n (%) | 12 (13) | 6 (10) | 6 (16) | 0.430 |
Indeterminate for UIP | n (%) | 33 (34) | 21 (36) | 12 (32) | 0.641 |
Alternative diagnosis | n (%) | 50 (52) | 30 (52) | 20 (52) | 0.931 |
TBLC | |||||
Diameter of the Cryoprobe | 1.9 mm, n (%) | 8 (8) | 3 (5) | 5 (13) | 0.166 |
2.4 mm, n (%) | 88 (92) | 55 (95) | 33 (87) | 0.166 | |
Number of specimens/patient | Mean (SD) | 4 (1) | 4 (1) | 4 (1) | 0.148 |
Size of specimens (mm2) | By specimen Mean (SD) | 21 (7) | 20 (7) | 22 (8) | 0.153 |
By patient Mean (SD) | 78 (24) | 74 (24) | 81 (24) | 0.138 | |
Final MDD diagnosis | |||||
IPF | n (%) | 35 (36) | 19 (33) | 16 (42) | 0.352 |
HP | n (%) | 34 (35) | 20 (34) | 14 (37) | 0.813 |
Other | n (%) | 27 (28) | 19 (33) | 8 (21) | 0.695 |