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Table 3 Diagnostic performance of baseline FEF50% % predicted for different cut-off values, obtained by ROC analysis to predict methacholine responsiveness (PC20 < 16 mg/ml)

From: Baseline spirometry parameters as predictors of airway hyperreactivity in adults with suspected asthma

Cut-off (%)

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

FEF50% %predicted

  < 120

99.10

10

11.40

99

  < 115

97.80

14.50

11.80

98.30

  < 110

96.60

19.30

12.30

97.90

  1. Sensitivity, specificity, positive predictive value (PPV), negative predicted value (NPV)