Table 1 IPA classification according to revised 2008 EORTC/MSG criteria
EORTC/MSG criteria | Host factors | Clinical criteria | Mycological criteria | Histopathological or cytopathological examination |
|---|---|---|---|---|
Recent history of neutropenia Receipt of an allogeneic stem cell transplant Prolonged use of corticosteroids Treatment with other recognized T cell immunosuppressants Inherited severe immunodeficiency URD* | The presence of 1 of the following 3 signs on CT: Dense, well-circumscribed lesion(s) with or without a halo sign An air-crescent sign A cavity | Positive culture and/or microscopy result for sputum, BALF, bronchial brush Positive serum or BALF GM tests | Histopathologic or direct microscopic demonstration | |
Possible IPA | √ | √ | ||
Probable IPA | √ | √ | √ | |
Proven IPA | √ |