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Table 2 The baseline data and prognosis of patients who received reintubation within 48 h of and 48 h after extubation in the two groups

From: Effects of high-flow oxygen therapy on patients with hypoxemia after extubation and predictors of reintubation: a retrospective study based on the MIMIC-IV database

  Treatment group n = 358 Control group n = 443
  All reintubations n = 79 Within 48 h n = 40 48 h after n = 39 P value All reintubations n = 81 Within 48 h n = 55 48 h after n = 26 P value
Age, median[Q1, Q3] 67.68[57.02, 78.00] 64.47[49.57, 77.97] 68.83[62.52, 77.59] 0.202 71.82[62.27, 78.93] 71.52[60.69, 78.69] 73.40[64.81, 78.74] 0.485
Male, n (%) 59(74.68) 31(77.50) 28(71.79) 0.746 48(59.26) 29(52.73) 19(73.08) 0.134
BMI, mean (SD) 29.65(5.87) 28.99(5.72) 30.38(6.02) 0.314 32.60(9.00) 31.12(8.34) 35.67(9.71) 0.051
Baseline disease
 Hypertension, n (%) 41(51.90) 18(45.00) 23(58.97) 0.309 54(66.67) 33(60.00) 21(80.77) 0.110
 Diabetes mellitus, n (%) 12(15.19) 7(17.50) 5(12.82) 0.790 13(16.05) 7(12.73) 6(23.08) 0.331
 COPD, n (%) 5(6.33) 3(7.50) 2(5.13) 1.000 9(11.11) 5(9.09) 4(15.38) 0.458
 Congestive heart failure, n (%) 23(29.11) 10(25.00) 13(33.33) 0.570 29(35.80) 17(30.91) 12(46.15) 0.277
 Myocardial infarction, n (%) 6(7.59) 4(10.00) 2(5.13) 0.675 14(17.28) 9(16.36) 5(19.23) 0.760
 Chronic kidney disease, n (%) 17(21.52) 5(12.50) 12(30.77) 0.089 21(25.93) 10(18.18) 11(42.31) 0.041
 Leukaemia, n (%) 1(1.27) 0 1(2.56) 0.494 2(2.47) 1(1.82) 1(3.85) 0.542
 Strokes, n (%) 8(10.13) 1(2.50) 7(17.95) 0.029 6(7.41) 4(7.27) 2(7.69) 1.000
 Cancer, n (%) 10(12.66) 6(15.00) 4(10.26) 0.737 16(19.75) 9(16.36) 7(26.92) 0.415
 Liver disease, n (%) 12(15.19) 7(17.50) 5(12.82) 0.790 14(17.28) 8(14.55) 6(23.08) 0.360
 SAPS-II at admission, mean (SD) 44.32(13.08) 43.30(10.86) 45.36(15.09) 0.490 47.20(13.72) 46.73(13.48) 48.19(14.45) 0.665
 Duration before extubation, median [Q1,Q3], hours 61.50[20.33, 125.27] 53.92[15.14, 110.82] 67.35[22.86, 138.07] 0.364 38.90[20.25, 131.67] 40.83[23.53, 128.29] 28.46[17.63, 127.40] 0.413
Physiological variables before extubation 4 h
 Heart rate, mean (SD) 87.28(15.55) 89.67(16.07) 84.84(14.80) 0.168 86.00(16.39) 87.03(14.03) 83.81(20.67) 0.476
 Respiratory rate, mean (SD) 19.10(4.67) 19.41(4.09) 18.78(5.23) 0.556 19.73(4.17) 19.70(4.42) 19.79(3.64) 0.920
 Tidal volume, mean (SD) 534.45(132.46) 527.92(146.70) 539.43(122.28) 0.734 454.31(111.36) 448.81(112.36) 466.35(110.87) 0.553
 MBP, mean (SD) 79.62(12.93) 81.10(13.91) 78.10(11.82) 0.304 77.45(10.11) 77.61(10.55) 77.13(9.31) 0.836
 pH, mean (SD) 7.41(0.07) 7.39(0.07) 7.42(0.06) 0.068 7.39(0.05) 7.39(0.06) 7.38(0.05) 0.831
 PaO2, median [Q1, Q3] 91.00[82.00, 107.00] 89.25[83.50, 104.62] 95.50[81.17, 110.50] 0.444 96.00[87.00, 108.00] 95.00[85.75, 106.25] 98.25[89.54, 115.00] 0.347
 PaCO2, mean (SD) 39.76(6.76) 39.52(6.60) 40.01(6.99) 0.751 44.79(10.47) 45.58(11.74) 43.10(7.01) 0.240
 SpO2, median [Q1, Q3] 97.00[95.54, 98.69] 96.50[95.00, 98.29] 97.25[96.38, 98.88] 0.088 97.25[95.50, 98.60] 97.80[95.75, 98.78] 96.50[95.56, 97.93] 0.172
 PaO2/FiO2, median [Q1,Q3] 209.00[175.50, 248.62] 208.00[170.00, 229.86] 217.50[189.75, 254.30] 0.233 220.00[187.50, 252.52] 213.00[186.50, 254.32] 221.88[192.12, 249.65] 0.712
 Mortality 28 days, n (%) 13(16.46) 4(10.00) 9(23.08) 0.206 12(14.81) 7(12.73) 5(19.23) 0.509