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Table 3 Patient demographic and clinical information

From: A comparison of diagnostic algorithms and clinical parameters to diagnose ventilator-associated pneumonia: a prospective observational study

Variable

All

VAP

n = 45

No VAP

n = 40

p-value

Age, years, mean (SD)

46.9 (18.9)

44.2 (20.7)

49.9 (16.4)

0.159a

Male, N (%)

62 (72.9)

33 (73.3)

29 (72.5)

0.931c

Admission indication, N (%)

0.652c

Trauma

54 (63.5)

30 (66.7)

24 (60)

Post-operative

31 (36.5)

15 (33.3)

16 (40)

Comorbidities, yes, N (%)

0.932b

ARDS

7 (8.2)

3 (6.7)

4 (10)

Cancer

13 (15.3)

6 (13.3)

7 (17.5)

COPD

7 (8.2)

4 (8.9)

3 (7.5)

CHF

24 (28.2)

13 (28.9)

11 (27.5)

ESRD

14 (16.5)

9 (20)

5 (12.5)

Multiple trauma

20 (23.5)

10 (22.2)

10 (25)

Positive tracheal culture, N (%)

69 (81.2)

40 (88.9)

29 (72.5)

0.093c

MDR organism, yes, N (%)

31 (36.5)

17 (37.8)

14 (35)

0.825c

Procalcitonin, ng/mL, mean (SD)

4.03 (4.68)

3.53 (3.6)

4.6 (5.6)

0.308a

APACHE II, mean (SD)

18.1 (2.84)

17.9 (3.43)

18.4 (1.98)

0.399a

Duration of intubation, hours, mean (SD)

177.1 (39.61)

176.02 (38.7)

178.32 (41.09)

0.791a

Reintubation, N (%)

32 (37.6)

14 (31.1)

18 (45)

0.262c

MV duration prior to VAP, hours, median (IQR)

72 (54–87.5)

72 (52–87.5)

72 (64.5–88.5)

0.639a

ICU duration prior to developing VAP, days, median (IQR)

7 (6–8)

7 (6–8.5)

7 (6–8)

0.118a

VAP timing, mean (SD)

Early (< 5 days)

–

15 (33.3)

–

–

Late (≥ 5 days)

 

30 (66.7)

  

Length-of-stay, days, mean (SD)

ICU LOS

9.8 (3.0)

13.13 (3.27)

12.72 (2.75)

0.538a

Non-ICU LOS

15.4 (3.1)

12.67 (3.34)

11.96 (2.99)

0.320a

Mortality, N (%)

ICU

17 (20)

8 (17.8)

9 (22.5)

0.787c

Hospital

22 (25.9)

12 (26.7)

10 (25)

0.861c

  1. VAP: ventilator-associated pneumonia; IQR: interquartile range; MDR: multiple drug resistant; APACHE: Acute Physiology and Chronic Health Evaluation; ICU: intensive care unit; VAP: ventilator-associated pneumonia; LOS: length-of-stay
  2. aIndependent sample t-test
  3. bFisher exact test
  4. cChi-square