Fig. 2
Distribution of patients above and below the cut-off values of the major predictors for the three adverse outcomes. Numbers within the bars are the patient counts. a KL-6 level versus nintedanib-related hepatic injury, b DLCO % predicted versus nintedanib-related hepatic injury, c KL-6 level versus on-treatment AE-IPF, d KL-6 level versus on-treatment mortality, and e SPA level versus on-treatment mortality. p-values were derived from Fisher’s exact test. Number of patients with available data: 54 for KL-6, 55 for DLCO % predicted, and 55 for SPA. Abbreviations AE-IPF, acute exacerbation of idiopathic pulmonary fibrosis; DLCO, diffusion capacity for carbon monoxide (in % predicted); KL-6, Krebs von den Lungen-6; SPA, surfactant protein A