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Fig. 5 | BMC Pulmonary Medicine

Fig. 5

From: ID1 mediates resistance to osimertinib in EGFR T790M-positive non-small cell lung cancer through epithelial–mesenchymal transition

Fig. 5

Flow cytometry analysis of apoptosis in osimertinib-sensitive and resistant cells. The apoptosis rate in H1975/OR cells was significantly decreased compared with that in osimertinib-sensitive cells (13.63 ± 1.72% versus 24.7 ± 0.78%). In H1975/OR + si-ID1 cells, the apoptosis rate was increased compared to H1975/OR cells (22.07 ± 1.03% versus 13.63 ± 1.72%), whereas in ID1 overexpressed H1975/OR + pcDNA3.0-ID1 cells, the apoptosis rate was further decreased (13.63 ± 1.72% versus 8.73 ± 1.94%). Representative results are shown from at least 3 independent experiments. *P < 0.05 versus H1975/OR

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BMC Pulmonary Medicine

ISSN: 1471-2466

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