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Fig. 5 | BMC Pulmonary Medicine

Fig. 5

From: EML4-ALK-mediated activation of the JAK2-STAT pathway is critical for non-small cell lung cancer transformation

Fig. 5

IL4 and IL6 affected the JAK2-STAT pathway in EML4-ALK-positive cells. a STAT3 and STAT6 were phosphorylated and translocated to the nuclei of H2228 cells following IL4 or IL6 treatment. b Microarray analysis of H2228 cells stimulated or not with IL4. The heat map identifies modified proteins associated with the JAK2-STAT pathway, the regulation of the actin cytoskeleton, the cell cycle, cell adhesion, and the positive regulation of cell proliferation

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BMC Pulmonary Medicine

ISSN: 1471-2466

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