Table 1 Patient characteristics of all included patients and each S100A4 group

Age, years (IQR)

74 (69–78)

72 (66–76)

74 (69–80)

Sex, male (%)

133 (82.1%)

44 (88.0%)

89 (79.5%)/

Respiratory function

FVC (L) (IQR)

2.90 (2.34–3.39)

2.99 (2.44–3.56)

2.88 (2.30–3.36)

VC (L) (IQR)

2.93 (2.40–3.37)

3.03 (2.50–3.51)

2.89 (2.34–3.25)

%VC (%) (IQR)

92.2 (81.1–101.4)

92.4 (79.3–102.3)

92.2 (82.8–101.4)

%DLCO (%) (IQR)

54.9 (44.6–68.1)

57.7 (43.2–76.6)

53.7 (44.8–67.6)

Serum KL-6 (U / ml) (IQR)

443 (290–739)

473 (272–945)

437 (317–660)

Collagen disease (%)

12 (7.4%)

5 (10.0%)

7 (6.3%)

Preoperative steroid use (%)

11 (6.8%)

5 (10.0%)

6 (5.4%)

Radiologic IP pattern

UIP pattern (%)

54 (33.3%)

18 (36.0%)

36 (32.1%)

Possible UIP pattern (%)

75 (46.3%)

23 (46.0%)

52 (46.4%)

Inconsistent with UIP Pattern (%)

33 (20.4%)

9 (18.0%)

24 (21.4%)

Clinical stage

0 (%)

4 (2.5%)

0 (0%)

4 (3.6%)

I (%)

128 (79.0%)

42 (84.0%)

86 (76.8%)

II (%)

21 (13.0%)

4 (8.0%)

17 (15.2%)

III (%)

9 (5.6%)

4 (8.0%)

5 (4.5%)

Histology

Adenocarcinoma (%)

65 (40.1%)

20 (40.0%)

45 (40.2%)

Squamous cell Carcinoma (%)

62 (38.3%)

18 (36.0%)

44 (39.3%)

Others (%)

35 (21.6%)

12 (24.0%)

23 (20.5%)

Surgical procedure

Wedge resection (%)

48 (29.6%)

12 (24.0%)

36 (32.1%)

Segmentectomy (%)

34 (21.0%)

13 (26.0%)

21 (18.8%)

Lobectomy (%)

79 (48.8%)

25 (50.0%)

54 (48.2%)

Pneumonectomy (%)

1 (0.6%)

0 (0%)

1 (0.9%)

Operative time (min) (IQR)

148 (107–190)

160 (121–207)

139 (104–182)

Pathological stage

I

118 (72.8%)

35 (70.0%)

83 (74.1%)

II

26 (16.0%)

8 (16.0%)

18 (16.1%)

III

17 (10.5%)

6 (12.0%)

11 (9.8%)

IV

1 (0.6%)

1 (2.0%)

0 (0%)