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Fig. 4 | BMC Pulmonary Medicine

Fig. 4

From: LINC01089 suppresses lung adenocarcinoma cell proliferation and migration via miR-301b-3p/STARD13 axis

Fig. 4

LINC01089 blocked LUAD progression via miR-301b-3p/STARD13 axis. a, b Co-transfection with sh-STARD13#1 or miR-301b-3p mimics could reverse the restraining effect of pcDNA3.1/LINC01089 on the proliferation ability of A549 cells according to the data from CCK-8 and EdU assays. c Silenced STARD13 or up-regulated miR-301b-3p could rescue the facilitating effect of LINC01089 up-regulation on cell apoptosis by flow cytometry analysis. d, e Co-transfection with sh-STARD13#1 or miR-301b-3p mimics could offset the suppressive effect of pcDNA3.1/LINC01089 on the migratory capability of A549 cells according to the data from Transwell and wound healing assays. The statistical analysis of Fig. 4a was assessed with two-way ANOVA. The statistical significance of Fig. 4b–e was analyzed with one-way ANOVA. *P < 0.05, **P < 0.01

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BMC Pulmonary Medicine

ISSN: 1471-2466

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