From: Risk factors for severe adult-onset asthma: a multi-factor approach
 | Non-severe asthma N = 1250 | Severe asthma N = 100 | P |
---|---|---|---|
Personal characteristics | |||
Female sex, n (%) | 793 (63.4) | 45 (45.0) |  < .001 |
Age, years, mean(SD) | 54.0 (12.2) | 58.7 (11.6) | .001 |
BMI1, mean (SD) | 26.9 (4.7) | 27.1 (5.5) | .94 |
Socio-economic characteristics | |||
Baccalaureate/secondary school, n (%) | 754 (61.8) | 71 (76.3) | .005 |
Professional training, n (%) | 296 (26.0) | 35 (40.7) | .004 |
Lifestyle factors | |||
Ever smokers, n (%) | 720 (57.6) | 74 (74.0) | .001 |
Early-life factors | |||
1st child, n (%) | 363 (29.0) | 22 (22.0) | .14 |
 ≥ 2 siblings, n (%) | 927 (75.9) | 84 (89.4) | .003 |
Growing up in the countryside/on a farm, n (%) | 937 (75.9) | 77 (80.2) | .39 |
Severe childhood infections2, n (%) | 217 (18.0) | 11 (11.7) | .13 |
Parental smoking, n (%) | 648 (51.8) | 53 (53.0) | .84 |
Parental asthma and/or allergy, n (%) | 437 (36.1) | 29 (29.9) | .23 |
Asthma characteristics | |||
NERD, n (%) | 124 (9.9) | 19 (19.0) | .007 |
Multimorbidity | |||
CRSwNP, n (%) | 145 (11.6) | 7 (7.0) | .19 |
 ≥ 1 other disease3, n (%) | 843 (67.4) | 86 (86.0) |  < .001 |
 ≥ 1 other allergic disease (AR/AC/AD), n (%) | 844 (67.5) | 63 (63.0) | .38 |