Table 2 Clinicopathological characteristics of MCD and IgG4-LD
From: IL-6 expression helps distinguish Castleman’s disease from IgG4-related disease in the lung
Factors | MCD (n = 6) | IgG4-LD (n = 4) | P value |
|---|---|---|---|
Age | 41.5 (38.5–50.75) | 69 (66.25–76.25) | 0.0139* |
Sex (male/female) | 4/2 | 3/1 | 0.7782 |
Serum IgG4 (mg/dL) | 304 (238.5–607.75) | 463.5 (250.75–1436.75) | 0.4555 |
Serum IL6 (pg/mL) | 25.3 (14–63) | 1.75 (0.83225–2.8725) | 0.0200* |
IL-6 H-score | 11.59 (7.18–17.92) | 5.605 (0.8625–9.7625) | 0.0662 |
IgG4/IgG ratio | 30.35 (25.475–57.6) | 80.8 (62.65–93.125) | 0.0142* |