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Table 4 Physiological and ventilator parameters in survivors and non-survivors

From: Cyclophosphamide for interstitial lung disease-associated acute respiratory failure: mortality, clinical response and radiological characteristics

 

Survivors

Non-survivors

p value

SOFA

8 (5–13)

11 (8–13)

0.241

P/F ratio 1 day before MPSa (mmHg)

156 (140–187)

122 (83–153)

0.119

P/F ratio 3 days after MPS (mmHg)

182 (156–221)

113 (99–187)

0.091

P/F ratio 1 day before CYC (mmHg)

129 (98–166)

113 (80–131)

0.214

P/F ratio 3 days after CYC (mmHg)

220 (159–270)

114 (69–207)

0.079

Cdyn 1 day before MPS (mL/cmH2O)

59 (34–87)

20 (17–42)

0.111

Cdyn 3 days after MPS (mL/cmH2O)

63 (51–91)

27 (14–61)

0.077

Cdyn 1 day before CYC (mL/cmH2O)

75 (41–126)

27 (8–63)

0.442

Cdyn 3 days after CYC (mL/cmH2O)

92 (52–151)

20 (9–36)

0.063

  1. Values are expressed as median and interquartile range (IQR)
  2. CYC, cyclophosphamide; Cdyn, dynamic compliance; MPS, methylprednisolone; P/F ratio, PaO2/FiO2-ratio; SOFA, Sequential Organ Failure Assessment;
  3. aMethylprednisolone 1 g/day for 3 days
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BMC Pulmonary Medicine

ISSN: 1471-2466

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