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Table 4 Correlations FRI versus 6MWT (n = 21)

From: Functional respiratory imaging in relation to classical outcome measures in cystic fibrosis: a cross-sectional study

  6MWT
6MWD (m) SpO2 start (%) SpO2 end (%)
FRI
 iVlobe at TLC (L) NS NS NS
 iVlobe at FRC (L) NS NS − 0.69***
 Log of siVaw at TLC (mL/L) NS NS NS
 Log of siVaww at TLC (mL/L) NS NS NS
 Log of siRaw at TLC (kPa*s/L) NS NS NS
 AT at FRC (%) − 0.85*** NS − 0.72***
 TBV at TLC (mL/L) NS NS NS
 BV10% at TLC (%) NS NS − 0.59**
 BV5_10% at TLC (%) NS NS − 0.60**
 Square of BV5% at TLC (%) NS NS 0.53*
CF-CT
 Total score − 0.53* NS − 0.73***
 Bronchiectasis NS NS − 0.72***
 Mucus plugging NS NS − 0.66**
 BWT NS NS NS
 Parenchyma − 0.45* NS NS
 AT NS NS − 0.71***
  1. FRI: Spearman correlation coefficients, only 6MWD was calculated using Pearson. CF-CT: Spearman correlation coefficients. *p < 0.05; **p < 0.01; ***p < 0.001
  2. iVlobe lobar volume, siVaw specific airway volume, siVaww specific airway wall volume, siRaw specific airway resistance, AT air trapping, TBV total pulmonary blood volume corrected for lobar volume, BV10% percentage of blood vessels larger than 10 mm2, BV5_10% percentage of blood vessels between 5 and 10 mm2, BV5% percentage of blood vessels smaller than 5 mm2, BWT bronchial wall thickening