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Table 1 Baseline data of the training group

From: Clinical-radiological predictive model in differential diagnosis of small (≤ 20 mm) solitary pulmonary nodules

 

Malignant (n = 156)

Benign (n = 94)

P value

Gender (male/female)

85/71

56/38

0.432

Age (y)

65.4

53.5

 < 0.001

Smoking history

72

38

0.377

Malignant history

5

1

0.519

CT features

Diameter (mm)

16.8

13.6

 < 0.001

Lobulation

114

49

0.001

Spiculation

120

47

 < 0.001

Pleural retraction sign

75

17

 < 0.001

CT bronchus sign

104

34

 < 0.001

Calcification

3

9

0.006

Mediastinal/hilar lymph nodule ≥ 10 mm

38

14

0.074

Lobes

  

0.951

Upper

67

40

 

Non-upper

89

54

 

Sides

  

0.897

Left

76

45

 

Right

80

49

 

Tumor markers

CEA (ug/L)

3.9

2.3

 < 0.001

Cyfra21-1 (ng/ml)

13.5

12.7

0.099

SCC (ug/L)

1.4

1.1

0.211

NSE (ng/ml)

2.5

2.4

0.423

  1. CEA: Carcinoembryonic antigen; CT: Computed tomography; NSE: Neuron-specific enolase; SCC: Squamous cell carcinoma antigen