Malignant (n = 156) | Benign (n = 94) | P value | |
---|---|---|---|
Gender (male/female) | 85/71 | 56/38 | 0.432 |
Age (y) | 65.4 | 53.5 | < 0.001 |
Smoking history | 72 | 38 | 0.377 |
Malignant history | 5 | 1 | 0.519 |
CT features | |||
Diameter (mm) | 16.8 | 13.6 | < 0.001 |
Lobulation | 114 | 49 | 0.001 |
Spiculation | 120 | 47 | < 0.001 |
Pleural retraction sign | 75 | 17 | < 0.001 |
CT bronchus sign | 104 | 34 | < 0.001 |
Calcification | 3 | 9 | 0.006 |
Mediastinal/hilar lymph nodule ≥ 10 mm | 38 | 14 | 0.074 |
Lobes | 0.951 | ||
Upper | 67 | 40 | |
Non-upper | 89 | 54 | |
Sides | 0.897 | ||
Left | 76 | 45 | |
Right | 80 | 49 | |
Tumor markers | |||
CEA (ug/L) | 3.9 | 2.3 | < 0.001 |
Cyfra21-1 (ng/ml) | 13.5 | 12.7 | 0.099 |
SCC (ug/L) | 1.4 | 1.1 | 0.211 |
NSE (ng/ml) | 2.5 | 2.4 | 0.423 |