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Table 1 Baseline data of the training group

From: Clinical-radiological predictive model in differential diagnosis of small (≤ 20 mm) solitary pulmonary nodules

  Malignant (n = 156) Benign (n = 94) P value
Gender (male/female) 85/71 56/38 0.432
Age (y) 65.4 53.5  < 0.001
Smoking history 72 38 0.377
Malignant history 5 1 0.519
CT features
Diameter (mm) 16.8 13.6  < 0.001
Lobulation 114 49 0.001
Spiculation 120 47  < 0.001
Pleural retraction sign 75 17  < 0.001
CT bronchus sign 104 34  < 0.001
Calcification 3 9 0.006
Mediastinal/hilar lymph nodule ≥ 10 mm 38 14 0.074
Lobes    0.951
Upper 67 40  
Non-upper 89 54  
Sides    0.897
Left 76 45  
Right 80 49  
Tumor markers
CEA (ug/L) 3.9 2.3  < 0.001
Cyfra21-1 (ng/ml) 13.5 12.7 0.099
SCC (ug/L) 1.4 1.1 0.211
NSE (ng/ml) 2.5 2.4 0.423
  1. CEA: Carcinoembryonic antigen; CT: Computed tomography; NSE: Neuron-specific enolase; SCC: Squamous cell carcinoma antigen