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Table 4 Predictors of severe CTEPH on univariable and multivariable analysis of CPET and PFT parameters

From: Cardiopulmonary exercise testing and pulmonary function testing for predicting the severity of CTEPH

Variables Univariate analysis Multivariate analysis
OR P 95% CI OR P 95% CI
VE @ AT (L/min) 1.169 0.004 1.051–1.300 1.162 0.024 1.020–1.323
PETCO2 @ AT (mm Hg) 0.809 0.005 0.698–0.938 1.023 0.901 0.713–1.469
VO2 @ peak (mL/kg/min) 0.627 0.005 0.452–0.870 0.633 0.026 0.423–0.948
LOWEST VE/VCO2 1.129 0.006 1.036–1.230 1.048 0.645 0.859–1.279
  1. Range for “Severe”: PAP (mm Hg) ≥ 45. CPET and PFT parameters were all analyzed with univariate logistic regression analysis, and 4 parameters with minimum P value entered in the multivariate logistic regression analysis. Results are expressed as odds ratio (OR) with 95% confidence interval (95% CI). VE = minute ventilation; VO2 = oxygen uptake; VCO2 = carbon dioxide output; PETCO2 = end-tidal partial pressure for carbon dioxide