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Table 4 Predictors of severe CTEPH on univariable and multivariable analysis of CPET and PFT parameters

From: Cardiopulmonary exercise testing and pulmonary function testing for predicting the severity of CTEPH

Variables

Univariate analysis

Multivariate analysis

OR

P

95% CI

OR

P

95% CI

VE @ AT (L/min)

1.169

0.004

1.051–1.300

1.162

0.024

1.020–1.323

PETCO2 @ AT (mm Hg)

0.809

0.005

0.698–0.938

1.023

0.901

0.713–1.469

VO2 @ peak (mL/kg/min)

0.627

0.005

0.452–0.870

0.633

0.026

0.423–0.948

LOWEST VE/VCO2

1.129

0.006

1.036–1.230

1.048

0.645

0.859–1.279

  1. Range for “Severe”: PAP (mm Hg) ≥ 45. CPET and PFT parameters were all analyzed with univariate logistic regression analysis, and 4 parameters with minimum P value entered in the multivariate logistic regression analysis. Results are expressed as odds ratio (OR) with 95% confidence interval (95% CI). VE = minute ventilation; VO2 = oxygen uptake; VCO2 = carbon dioxide output; PETCO2 = end-tidal partial pressure for carbon dioxide