Table 3 Exacerbation severity and treatment by baseline biomarker profile
| Â | Number of exacerbation | Hospitalized exacerbation N (%) | p-value | Exacerbation treated with antibiotics N (%) | p-value | Exacerbation treated with systemic corticosteroids N (%) | p-value |
|---|---|---|---|---|---|---|---|
LPA16:0 | |||||||
 Low | 32 | 6 (18.8) |  | 28 (87.5) |  | 29 (90.6) |  |
 Medium | 31 | 4 (12.9) | 0.42 | 23 (74.2) | 0.058 | 29 (93.5) | 0.89 |
 High | 19 | 1 (5.3) |  | 11 (57.9) |  | 17 (89.5) |  |
LPA18:0 | |||||||
 Low | 31 | 4 (12.9) |  | 24 (77.4) |  | 28 (90.3) | 1.0 |
 Medium | 30 | 5 (16.7) | 0.85 | 24 (80.0) | 0.58 | 28 (93.3) |  |
 High | 21 | 2 (9.5) |  | 14 (66.7) |  | 19 (90.5) |  |
LPA18:1 | |||||||
 Low | 25 | 2 (8.0) |  | 22 (88.0) |  | 22 (88.0) |  |
 Medium | 34 | 7 (20.6) | 0.36 | 26 (76.5) | 0.10 | 33 (97.1) | 0.32 |
 High | 23 | 2 (8.7) |  | 14 (60.9) |  | 20 (87.0) |  |
LPA18:2 | |||||||
 Low | 29 | 4 (13.8) |  | 21 (72.4) |  | 27 (93.1) |  |
 Medium | 30 | 4 (13.3) | 1.0 | 26 (86.7) | 0.18 | 27 (90.0) | 1.0 |
 High | 23 | 3 (13.0) |  | 15 (65.2) |  | 21 (91.3) |  |
LPA20:4 | |||||||
 Low | 32 | 5 (15.6) |  | 25 (78.1) |  | 29 (90.6) |  |
 Medium | 33 | 4 (12.1) | 0.92 | 24 (72.7) | 0.944 | 33 (100) | 0.0087* |
 High | 17 | 2 (11.8) |  | 13 (76.5) |  | 13 (76.5) |  |