Differences in genetics and microenvironment of lung adenocarcinoma patients with or without TP53 mutation

BMC Pulmonary Medicine

Table 1 Clinical features of the TCGA samples

Characteristics	Mutation (N = 235)		Wild (N = 274)		p value
Characteristics	N	%	N	%	p value
Age					0.005
≤ 65	127	54.04	109	39.78
> 65	102	43.41	153	55.84
NA	6	2.55	12	4.38
Sex					0.994
Male	109	46.38	127	46.35
Female	126	53.62	147	53.65
Stage					0.630
Stage I	120	51.06	155	56.57
Stage II	60	25.53	59	21.54
Stage III	38	16.17	45	16.42
Stage IV	14	5.96	11	4.01
NA	3	1.28	4	1.46
T					0.565
T1	75	31.91	93	33.94
T2	131	55.74	145	52.92
T3	19	8.09	25	9.12
T4	8	3.40	11	4.01
NA	2	0.85	0	0.00
M					0.190
M0	150	63.83	195	71.17
M1	14	5.96	11	4.01
NA	71	30.21	68	24.82
N					0.384
N0	146	62.13	180	65.69
N1	50	21.28	47	17.15
N2	33	14.04	40	14.60
N3	2	0.85	0	0.00
NA	4	1.70	7	2.55

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