Skip to main content

Table 2 Baseline demographic and clinical characteristics of patients with cryptogenic and secondary organizing pneumonia

From: Comparison of clinical features and prognosis in patients with cryptogenic and secondary organizing pneumonia

 

COP (n = 16)

SOP (n = 69)

Total OP (n = 85)

P

Age, years

64 (62–74)

71 (61–78)

70.0 (61–77)

0.303

Male:female

11:5

58:11

69:16

0.158

Smoking

   

0.533

 Non-smoker

6 (37.5)

25 (36.2)

31 (36.5)

 

 Ex-smoker

6 (37.5)

34 (49.3)

40 (47.1)

 

 Smoker

4 (25.0)

10 (14.5)

14 (16.5)

 

Reason for biopsy

   

0.126

 Pneumonic lesion

9 (56.3)

52 (75.4)

61 (71.8)

 

 Mass lesion

7 (43.8)

17 (24.6)

24 (28.2)

 

Duration between first visit and biopsy, days

13 (9–23)

13 (8–20)

13 (8–20)

0.875

BMI, kg/m2

24.1 (21.3–25.5)

21.7 (19.7–24.2)

22.0 (19.8–24.5)

0.030**

Symptom duration, weeks

4 (2–5) (n = 13)

1 (1–4) (n = 63)

2 (1–4) (n = 76)

0.006**

Symptom

    

 Cough

12 (75.0)

50 (72.5)

62 (72.9)

0.837

 Sputum

9 (56.3)

37 (53.6)

46 (54.1)

0.849

 Dyspnea

9 (56.3)

25 (36.2)

34 (40.0)

0.141

 Fever

2 (6.3)

30 (43.5)

32 (37.6)

0.024*

 Hemoptysis

2 (12.5)

6 (8.7)

8 (9.4)

0.641

 Chest pain

3 (18.8)

3 (4.3)

6 (7.1)

0.078

 Mental status change

0

3 (4.3)

3 (3.5)

0.539

Underlying diseases

    

 Hypertension

4 (25.0)

31 (44.9)

35 (41.2)

0.170

 Diabetes mellitus

4 (25.0)

22 (31.9)

26 (30.6)

0.766

 Chronic airway disease

3 (18.8)

15 (21.7)

18 (21.2)

0.547

 Ischemic heart disease

2 (12.5)

11 (15.9)

13 (15.3)

0.539

 Cerebrovascular disease

0

11 (15.9)

11 (12.9)

0.115

 Active cancer

1 (6.3)

7 (10.1)

8 (9.4)

0.532

 Immune suppression

0

7 (10.1)

7 (8.2)

0.338

 Bed bound state

0

7 (10.1)

7 (8.2)

0.338

 Atrial fibrillation

2 (12.5)

4 (5.8)

6 (7.1)

0.315

 Chronic kidney disease

0

5 (7.2)

5 (5.9)

0.578

 Chronic liver disease

3 (18.8)

1 (1.4)

4 (4.7)

0.020*

 Other interstitial lung diseases

0

1 (1.4)

1 (1.2)

0.812

 Connective tissue diseases

0

1 (1.4)

1 (1.2)

0.812

CURB-65 [25]

   

0.017***

 0

7 (43.8)

12 (17.4)

19(22.4)

 

 1

7 (43.8)

29 (42.0)

36(42.4)

 

 2

2 (12.5)

20 (29.0)

22(25.9)

 

 3

0

7 (10.1)

7(8.2)

 

 4

0

1 (1.4)

1(1.2)

 
  1. Data are presented as number (%) or median (interquartile range [IQR])
  2. COP cryptogenic organizing pneumonia, SOP secondary organizing pneumonia, OP organizing pneumonia, BMI body mass index
  3. *P < 0.05 by chi-square tests or Fisher’s exact tests for comparisons between the COP and SOP groups
  4. **P < 0.05 by Mann–Whitney U-tests for comparisons between the COP and SOP groups
  5. ***P < 0.05 by linear-by-linear association for comparisons between the COP and SOP groups