Table 1 Demographics stratified by high/normal/low compliance
From: Trajectories of hypoxemia and pulmonary mechanics of COVID-19 ARDS in the NorthCARDS dataset
All patients with reliable compliance (n = 1536) | Patients with very low compliance (< 20 ml/cm H2O) (n = 531; 34.6%) | Patients with low–normal compliance (20–50 ml/cm H2O) (n = 970; 63.2%) | Patients with high compliance (> 50 ml/cm H2O) (n = 35; 2.2%) | p value (very low vs. low–normal compliance) | |
|---|---|---|---|---|---|
Age median (IQR) | 65.0 (56.0,73.0) | 64.0 (56.0,73.0) | 65.0 (56.0,74.0) | 69.0 (60.5,73.0) | 0.042 |
Female n (%) | 485 (31.6) | 232 (43.7) | 242 (24.9) | 11 (31.4) | < 0.001 |
Race | |||||
African American/Black n (%) | 284 (18.5%) | 111 (20.9%) | 168 (17.3%) | 5 (14.3%) | 0.088 |
Asian n (%) | 152 (9.9%) | 68 (12.8%) | 82 (8.5%) | 2 (5.7%) | 0.007 |
Other/Multiracial n (%) | 481 (31.3%) | 189 (35.6%) | 274 (28.2%) | 18 (51.4%) | 0.003 |
White n (%) | 537 (35.0%) | 138 (26.0%) | 391 (40.3%) | 8 (22.9%) | < 0.001 |
Unknown n (%) | 82 (5.3%) | 25 (4.7%) | 55 (5.7%) | 2 (5.7%) | 0.428 |
Comorbidities | |||||
Charlson Index mean (SD) | 4.9 (3.2) | 4.7 (3.2) | 5.0 (3.3) | 4.4 (2.2) | 0.178 |
MEWS on admission mean (SD) | 4.1 (1.9) | 4.2 (1.9) | 4.1 (1.9) | 3.9 (1.6) | 0.224 |
BMI on admission mean (SD) | 31.0 (7.1) | 30.5 (7.4) | 31.3 (7.0) | 29.4 (4.3) | 0.035 |
Chronic lung Disease n (%) | 104 (6.8%) | 35 (6.6%) | 67 (6.9%) | 2 (5.7%) | 0.816 |
Diabetes n (%) | 666 (43.4%) | 232 (43.7%) | 419 (43.2%) | 15 (42.9%) | 0.853 |
HTN n (%) | 1001 (65.2%) | 345 (65.0%) | 638 (65.8%) | 18 (51.4%) | 0.755 |
CHF n (%) | 115 (7.5%) | 36 (6.8%) | 77 (7.9%) | 2 (5.7%) | 0.416 |
CAD n (%) | 204 (13.3%) | 56 (10.5%) | 144 (14.8%) | 4 (11.4%) | 0.019 |
CKD n (%) | 226 (14.7%) | 67 (12.6%) | 156 (16.1%) | 3 (8.6%) | 0.071 |
ESRD n (%) | 81 (5.3%) | 25 (4.7%) | 55 (5.7%) | 1 (2.9%) | 0.428 |
Positive Smoking n (%) | 197 (12.8%) | 64 (12.1%) | 131 (13.5%) | 2 (5.7%) | 0.424 |
Malignancy n (%) | 146 (9.5%) | 50 (9.4%) | 93 (9.6%) | 3 (8.6%) | 0.914 |
Altered mental status 24 h before intubation n (%) | 388 (25.3%) | 120 (22.6%) | 257 (26.5%) | 11 (31.4%) | 0.096 |
BMI categories | |||||
BMI < 18 underweight n (%) | 9 (0.6%) | 7 (1.3%) | 2 (0.2%) | 0 (0.0%) | 0.008 |
BMI 18 to < 30 normal–overweight n (%) | 733 (47.7%) | 263 (49.5%) | 453 (46.7%) | 17 (48.6%) | 0.294 |
BMI 30 to < 40 obese n (%) | 550 (35.8%) | 185 (34.8%) | 350 (36.1%) | 15 (42.9%) | 0.631 |
BMI ≥ 40 extremely obese n (%) | 244 (15.9%) | 76 (14.3%) | 165 (17.0%) | 3 (8.6%) | 0.173 |