Parameter | SP sign of negative pre-BPTs | ||||
---|---|---|---|---|---|
(Vol A − Vol B) × 100/FVC ratio (≤ 10%) (N = 50) | (Vol A − Vol B) × 100/FVC ratio (> 10% to ≤ 20%) (N = 50) | (Vol A − Vol B) × 100/FVC ratio (> 20% to ≤ 30%) (N = 50) | (Vol A − Vol B) × 100/FVC ratio (> 30%) (N = 50) | P value | |
Age, years | 39.1 ± 2.2 | 41.9 ± 2.2 | 40.6 ± 1.8 | 37.7 ± 2.0 | .797 |
Sex, n (%) | .002 | ||||
Male | 31 (62%)c,d | 25 (50%) | 14 (28%)a | 17 (34%)a | |
Female | 19 (38%)c,d | 25 (50%) | 36 (72%)a | 33 (66%)a | |
BMI, kg/m2 | 22.4 (19.8, 24.3) | 22.4 (19.9, 24.5) | 22.4 (20.2, 25.2) | 21.3 (20.2, 24.6) | .884 |
Obesity, n (%) (BMI ≥ 30 kg/m2) | 0/50 (0%) | 2/50 (4%) | 2/50 (4%) | 2/50 (4%) | .727 |
Underweight, n (%) (BMI < 18.5 kg/m2) | 5/50 (10%) | 5/50 (10%) | 5/50 (10%) | 5/50 (10%) | 1.000 |
Smoking status, n (%) | .005 | ||||
Current or former smoker | 17 (34%)d | 7 (14%) | 5 (10%) | 6 (12%)a | |
Never smoker | 33 (66%)d | 43 (86%) | 45 (90%) | 44 (88%)a | |
FVC % predicted, % | 102.5 (95.3, 108.2) | 101.7 (92.4, 111.1) | 104.1 (98.1, 113.3) | 106.3 (95.1, 115.4) | .200 |
FEV1% predicted, % | 97.7 (91.9, 103.3)d | 98.0 (91.9, 108.0) | 102.6 (96.0, 112.5) | 105.2 (98.1, 111.4)a | .007 |
FEV1/FVC ratio | 0.81 ± 0.01d | 0.82 ± 0.01 | 0.83 ± 0.01 | 0.85 ± 0.01a | .003 |
Chronic cough, n (%) | < .0001 | ||||
Rare | 6 (12%)d | 11 (22%) | 5 (10%) | 26 (52%)a | |
Sometimes | 44 (88%)d | 39 (78%) | 45 (90%) | 24 (48%)a | |
Sputum production, n (%) | 24/50 (48%) | 24/50 (48%) | 22/50 (44%) | 24/50 (48%) | .971 |
Chest tightness, n (%) | 0/50 (0%) | 0/50 (0%) | 0/50 (0%) | 1/50 (2%) | 1.000 |
Wheezing, n (%) | 15/50 (30%) | 14/50 (28%) | 8/50 (16%) | 16/50 (32%) | .264 |
PFT indication, n (%) | |||||
Asthma | 7 (14%) | 8 (16%) | 6 (12%) | 2 (4%) | .253 |
COPD | 10 (20%)d | 3 (6%) | 0 (0%) | 1 (2%)a | < .0001 |
ILD | 0 (0%) | 2 (4%) | 0 (0%) | 0 (0%) | .246 |
Pulmonary nodule/neoplasia | 1 (2%) | 2 (4%) | 1 (2%) | 0 (0%) | .903 |
Cough | 26 (52%) | 28 (56%) | 28 (56%) | 29 (58%) | .943 |
Shortness of breath | 1 (2%) | 1 (2%) | 2 (4%) | 3 (6%) | .839 |
Rhinitis/sinusitis | 5 (10%) | 2 (4%) | 5 (10%) | 2 (4%) | .477 |
Othere | 0 (0%)d | 4 (8%) | 8 (16%) | 13 (26%)a | .001 |