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Table 6 Baseline characteristics of the SP width-stratified classes in negative pre-BPTs

From: Clinical analysis of the “small plateau” sign on the flow-volume curve followed by deep learning automated recognition

Parameter

SP sign of negative pre-BPTs

(Vol A − Vol B) × 100/FVC ratio

(≤ 10%)

(N = 50)

(Vol A − Vol B) × 100/FVC ratio

(> 10% to ≤ 20%)

(N = 50)

(Vol A − Vol B) × 100/FVC ratio

(> 20% to ≤ 30%)

(N = 50)

(Vol A − Vol B) × 100/FVC ratio

(> 30%)

(N = 50)

P value

Age, years

39.1 ± 2.2

41.9 ± 2.2

40.6 ± 1.8

37.7 ± 2.0

.797

Sex, n (%)

    

.002

 Male

31 (62%)c,d

25 (50%)

14 (28%)a

17 (34%)a

 

 Female

19 (38%)c,d

25 (50%)

36 (72%)a

33 (66%)a

 

BMI, kg/m2

22.4 (19.8, 24.3)

22.4 (19.9, 24.5)

22.4 (20.2, 25.2)

21.3 (20.2, 24.6)

.884

Obesity, n (%)

(BMI ≥ 30 kg/m2)

0/50 (0%)

2/50 (4%)

2/50 (4%)

2/50 (4%)

.727

Underweight, n (%)

(BMI < 18.5 kg/m2)

5/50 (10%)

5/50 (10%)

5/50 (10%)

5/50 (10%)

1.000

Smoking status, n (%)

    

.005

 Current or former smoker

17 (34%)d

7 (14%)

5 (10%)

6 (12%)a

 

 Never smoker

33 (66%)d

43 (86%)

45 (90%)

44 (88%)a

 

FVC % predicted, %

102.5 (95.3, 108.2)

101.7 (92.4, 111.1)

104.1 (98.1, 113.3)

106.3 (95.1, 115.4)

.200

FEV1% predicted, %

97.7 (91.9, 103.3)d

98.0 (91.9, 108.0)

102.6 (96.0, 112.5)

105.2 (98.1, 111.4)a

.007

FEV1/FVC ratio

0.81 ± 0.01d

0.82 ± 0.01

0.83 ± 0.01

0.85 ± 0.01a

.003

Chronic cough, n (%)

    

< .0001

 Rare

6 (12%)d

11 (22%)

5 (10%)

26 (52%)a

 

 Sometimes

44 (88%)d

39 (78%)

45 (90%)

24 (48%)a

 

Sputum production, n (%)

24/50 (48%)

24/50 (48%)

22/50 (44%)

24/50 (48%)

.971

Chest tightness, n (%)

0/50 (0%)

0/50 (0%)

0/50 (0%)

1/50 (2%)

1.000

Wheezing, n (%)

15/50 (30%)

14/50 (28%)

8/50 (16%)

16/50 (32%)

.264

PFT indication, n (%)

     

 Asthma

7 (14%)

8 (16%)

6 (12%)

2 (4%)

.253

 COPD

10 (20%)d

3 (6%)

0 (0%)

1 (2%)a

< .0001

 ILD

0 (0%)

2 (4%)

0 (0%)

0 (0%)

.246

 Pulmonary nodule/neoplasia

1 (2%)

2 (4%)

1 (2%)

0 (0%)

.903

 Cough

26 (52%)

28 (56%)

28 (56%)

29 (58%)

.943

 Shortness of breath

1 (2%)

1 (2%)

2 (4%)

3 (6%)

.839

 Rhinitis/sinusitis

5 (10%)

2 (4%)

5 (10%)

2 (4%)

.477

 Othere

0 (0%)d

4 (8%)

8 (16%)

13 (26%)a

.001

  1. Data are presented as absolute numbers (percentages) in case of frequencies, median values, and quartiles in case of continuous parameters unless otherwise noted. Statistical comparisons based on percent predicted (pp) unless otherwise noted for pulmonary function test (PFT) values
  2. aP < 0.05; (Vol A − Vol B) × 100/FVC ratio ≤ 10% versus the remaining groups 
  3. bP < 0.05; (Vol A − Vol B) × 100/FVC ratio > 10% to ≤ 20% versus the remaining groups
  4. cP < 0.05; (Vol A − Vol B) × 100/FVC ratio > 20% to ≤ 30% versus the remaining groups
  5. dP < 0.05; (Vol A − Vol B) × 100/FVC ratio > 30% versus the remaining groups
  6. eIndications include bronchiectasis, chest pain, pleural effusion, sleep disorder, and studies without documented indication
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