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Table 4 Comparison of clinical findings of patients with MEPE and non-MEPE, peripheral eosinophilia and normal peripheral eosinophil

From: Incidence, aetiology and clinical features of eosinophilic pleural effusion: a retrospective study

  Total (n = 34) MEPE vs non-MEPE Peripheral eosinophilia vs normal peripheral eosinophil
MEPE (n = 18) Non-MEPE (n = 16) p-Value Peripheral eosinophilia (n = 9) Normal peripheral eosinophil (n = 25) p-Value
Age (y) 56.4 (25–88) 61.7 (44–88) 50.5 (25–83) 0.03 51.7 (25–74) 58.1 (29–88) 0.36
Sex     0.774    0.70
Male 20 (58.82%) 11 (61.11%) 9 (77.8%)   6 (66.7%) 14 (56.0%)  
Female 14 (41.18%) 7 (38.89%) 7 (22.2%)   3 (33.3%) 11 (44.0%)  
Peripheral blood
WBC (× 109/L) 8.6 (3.2–21.4) 8.5 (3.2–21.4) 8.8 (4.6–16.7) 0.87 10.1 (4.7–16.7) 8.1 (3.2–21.4) 0.04
LYM (× 109/L) 1.3 (0.3–2.5) 1.4 (0.6–2.5) 1.2 (0.3–2.4) 0.26 1.5 (0.3–2.4) 1.2 (0.5–2.5) 0.13
EO (× 106/L) 514.7 (0–5778.0) 394.4 (0–1500.0) 661.2 (0–5778.0) 0.44 1378.0 (600–5778.0) 204.0 (0–500)  < 0.001
Pleural effusion
LDH (U/L) 369 (90–1402) 449 (172–1402) 280 (90–667) 0.09 437 (128–1126) 345 (90- 1402) 0.51
GLU (mmol/L) 6.07 (3.02–9.77) 6.50 (4.32–9.77) 5.60 (3.02–8.0) 0.12 5.93 (3.02–9.77) 6.12 (3.19–8.34) 0.54
Protein (g/L) 48.0 (27.5–182.9) 55.4 (35.2–182.9) 39.7 (27.5–53.4) 0.07 45.8 (32.8–62.3) 48.8 (27.5–182.9) 0.73
ADA (U/L) 10.4 (0.1–44.7) 8.4 (3.0–29.3) 12.6 (0.1–44.7) 0.24 10.4 (2.8–29.3) 10.4 (0.1–44.7) 0.79
CEA (ng/mL) 106.4 (0.3–2087.0) 199.0 (0.5–2087.0) 2.2 (0.3–4.8) 0.11 24.9 (0.30–162.2) 135.7 (1.0–2087.0) 0.32
WBC (× 109/L) 3.2 (0.1–12.9) 1.8 (0.1–7.67) 4.7 (0.3–12.9) 0.01 5.01 (0.3–12.9) 2.50 (0.1–7.4) 0.10
EO (%) 21.7 (10.0–67.5) 20.6 (10.0–63.0) 22.9 (11.6–67.5) 0.66 31.8 (11.0–67.5) 18.1 (10–46.5) 0.16
RBC (× 109/L) 111.2 (0.2–2986.7) 41.0 (0.2–320) 190.3 (0.2–2986.7) 0.40 27.9 (0.2–216.2) 141.3 (0.2–2986.7) 0.14
  1. Data are presented as the mean (range) or n (%). MEPE malignant eosinophilic pleural effusion, WBC white blood cell, LYM lymphocyte, EO eosinophil, RBC red blood cell, LDH lactate dehydrogenase, ADA adenosine deaminase, GLU glucose, CEA carcinoembryonic antigen