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Table 3 Performance of the computer-aided detection system in different subgroups

From: Deep learning computer-aided detection system for pneumonia in febrile neutropenia patients: a diagnostic cohort study

Patient groups

AUC

Sensitivity

Specificity

All patients (n = 525)

0.892 (0.851–0.926)

88.3% (113/128, 82.7–93.9%)

68.3% (271/397, 63.7%–72.8%)

Patients with chest CT scan (n = 122)

0.852 (0.776–0.909)

83.8% (57/68, 75.1–92.6%)

59.3% (32/54, 46.2–72.4%)

Patients without chest CT scan (n = 403)

0.917 (0.886–0.942)

93.3% (56/60, 87.0–99.6%)

69.7% (239/343, 64.8–74.5%)

P valuea

0.099

0.095

0.126

Men (n = 291)

0.892 (0.851–0.926)

88.9% (64/72, 81.6–96.1%)

69.4% (152/219, 63.3–75.5%)

Women (n = 234)

0.899 (0.853–0.934)

87.5% (49/56, 78.8–96.2%)

66.9% (119/178, 59.9–73.8%)

P valueb

0.854

0.809

0.587

Age < 60 years (n = 286)

0.906 (0.866–0.937)

86.2% (50/58, 77.3–95.1%)

79.8% (182/228, 74.6–85.0%)

Age ≥ 60 years (n = 239)

0.867 (0.818–0.908)

90.0% (63/70, 83.0–97.0%)

52.7% (89/169, 45.1–60.2%)

P valuec

0.300

0.507

 < 0.001

CXRs from a fixed scanner (n = 146)

0.899 (0.838–0.943)

87.5% (21/24, 74.3–100%)

79.5% (97/122, 72.3–86.7%)

CXRs from a portable scanner (n = 379)

0.889 (0.853–0.919)

88.5% (92/104, 82.3–94.6%)

63.3% (174/275, 57.3–68.9%)

P valued

0.831

0.895

0.001

  1. Numbers in parentheses indicate numerators/denominators, 95% confidence intervals
  2. AUC, area under the receiver operating characteristic curve; CT, computed tomography; CXR, chest X-ray
  3. aComparison of performance between patients with and without a chest CT scan
  4. bComparison of performance between men and women
  5. cComparison of performance between patients aged < 60 years and those aged ≥ 60 years
  6. dComparison of performance between CXRs from a fixed scanner and CXRs from a portable scanner
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BMC Pulmonary Medicine

ISSN: 1471-2466

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