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Table 3 Performance of the computer-aided detection system in different subgroups

From: Deep learning computer-aided detection system for pneumonia in febrile neutropenia patients: a diagnostic cohort study

Patient groups AUC Sensitivity Specificity
All patients (n = 525) 0.892 (0.851–0.926) 88.3% (113/128, 82.7–93.9%) 68.3% (271/397, 63.7%–72.8%)
Patients with chest CT scan (n = 122) 0.852 (0.776–0.909) 83.8% (57/68, 75.1–92.6%) 59.3% (32/54, 46.2–72.4%)
Patients without chest CT scan (n = 403) 0.917 (0.886–0.942) 93.3% (56/60, 87.0–99.6%) 69.7% (239/343, 64.8–74.5%)
P valuea 0.099 0.095 0.126
Men (n = 291) 0.892 (0.851–0.926) 88.9% (64/72, 81.6–96.1%) 69.4% (152/219, 63.3–75.5%)
Women (n = 234) 0.899 (0.853–0.934) 87.5% (49/56, 78.8–96.2%) 66.9% (119/178, 59.9–73.8%)
P valueb 0.854 0.809 0.587
Age < 60 years (n = 286) 0.906 (0.866–0.937) 86.2% (50/58, 77.3–95.1%) 79.8% (182/228, 74.6–85.0%)
Age ≥ 60 years (n = 239) 0.867 (0.818–0.908) 90.0% (63/70, 83.0–97.0%) 52.7% (89/169, 45.1–60.2%)
P valuec 0.300 0.507  < 0.001
CXRs from a fixed scanner (n = 146) 0.899 (0.838–0.943) 87.5% (21/24, 74.3–100%) 79.5% (97/122, 72.3–86.7%)
CXRs from a portable scanner (n = 379) 0.889 (0.853–0.919) 88.5% (92/104, 82.3–94.6%) 63.3% (174/275, 57.3–68.9%)
P valued 0.831 0.895 0.001
  1. Numbers in parentheses indicate numerators/denominators, 95% confidence intervals
  2. AUC, area under the receiver operating characteristic curve; CT, computed tomography; CXR, chest X-ray
  3. aComparison of performance between patients with and without a chest CT scan
  4. bComparison of performance between men and women
  5. cComparison of performance between patients aged < 60 years and those aged ≥ 60 years
  6. dComparison of performance between CXRs from a fixed scanner and CXRs from a portable scanner