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Table 6 Univariable and multivariable analysis of risk factors for DR-TB in normal weight cases

From: Association between body mass index and newly diagnosed drug-resistant pulmonary tuberculosis in Shandong, China from 2004 to 2019

Characteristics Non-DR n = 5207 (%) DR-TB n = 1210 (%) Univariable analysis Multivariable analysis
OR (95% CI) P value OR (95% CI) P value
Age (years) (n = 5186/n = 1206)       
0–14 10 (0.19%) 2 (0%) 0.868 (0.189–3.997) 0.856 0.96 (0.209–4.459) 0.963
15–24 812 (15.66%) 187 (0.26%) Reference Reference Reference Reference
25–44 1356 (26.15%) 369 (0.52%) 1.182 (0.971–1.438) 0.096 1.17 (0.961–1.426) 0.118
45–64 1780 (34.32%) 407 (0.57%) 0.993 (0.819–1.203) 0.942 0.95 (0.781–1.159) 0.622
 > 65 1228 (23.68%) 241 (0.34%) 0.852 (0.69–1.052) 0.137 0.829 (0.667–1.03) 0.091
Sex (n = 5207/n = 1210)       
Female 918 (17.63%) 185 (15.29%) Reference Reference Reference Reference
Male 4289 (82.37%) 1025 (84.71%) 1.186 (0.998–1.408) 0.052 1.26 (1.059–1.513) 0.010*
Cavity (n = 4624/n = 1065)       
No 2640 (57.09%) 565 (53.05%) Reference Reference Reference Reference
Yes 1984 (42.91%) 500 (46.95%) 0.86 (0.702–1.054) 0.147 1.15 (1.006–1.319) 0.040*
Smoking (n = 4188/n = 949)       
No 3125 (74.62%) 722 (76.08%) Reference Reference Reference Reference
Yes 1063 (25.38%) 227 (23.92%) 0.924 (0.784–1.09) 0.348 0.984 (0.79–1.226) 0.887
Drinking (n = 4160/n = 943)       
No 3257 (78.29%) 758 (80.38%) Reference Reference Reference Reference
Yes 903 (21.71%) 185 (19.62%) 0.88 (0.738–1.051) 0.158 0.858 (0.68–1.084) 0.2
Co-morbidity (n = 5207/n = 1210)       
No 4665 (89.59%) 1074 (88.76%) Reference Reference Reference Reference
COPD 94 (1.81%) 20 (1.65%) 0.91 (0.562–1.487) 0.718 0.938 (0.5–1.76) 0.843
Diabetes 354 (6.8%) 97 (8.02%) 1.195 (0.946–1.51) 0.136 1.23 (0.969–1.568) 0.089
Hypertension 98 (1.88%) 19 (1.57%) 0.83 (0.507–1.365) 0.466 0.91 (0.548–1.514) 0.72
Other co-morbidity 216 (4.15%) 51 (4.21%) 1.01 (0.744–1.389) 0.917 1.11 (0.746–1.667) 0.596
  1. DR-TB, drug-resistant tuberculosis; aOR, adjusted odds ratio; OR, odds ratio; COPD, chronic obstructive pulmonary disease
  2. *P < 0.05; Normal weight: 18.5 kg/m2 ≥ BMI ≤ 24.9 kg/m2