Fig. 5

Establishment of a 5-DEAS-based OS signature. A The forest plot of the univariate Cox analyses. B LASSO coefficient profiles of the candidate survival-related DEASs. A coefficient profile plot was produced against the log λ sequence related to OS. C Dotted vertical lines were drawn at the optimal values using the minimum criteria related to OS. D ROC curve analysis to evaluate the sensitivity and specificity of the gene signature. E K–M survival curve to test the predictive effect of the gene signature. F DEAS expression levels of the high-risk and low-risk groups with the OS signatures. G OS scatter plots for LUAD patients. H Risk score distribution of patients with the OS signatures