Vascular involvement in chronic thromboembolic pulmonary hypertension is associated with spirometry obstructive impairment

Table 3 The correlation between PFT parameters and pulmonary hemodynamic parameters, CTA score at initial diagnosis

	%FEV_1.0		%MMF		%\({\dot{\text{V}}}\)50		%\({\dot{\text{V}}}\)25
	r	p	r	p	r	p	r	p
mPAP	− 0.266	0.002*	− 0.204	0.0177*	− 0.271	0.0015*	− 0.194	0.0244*
PVR	− 0.284	0.0009**	− 0.223	0.0096**	− 0.241	0.0051	− 0.195	0.0245*
CO	0.127	0.1408	0.176	0.0410*	0.137	0.113	0.152	0.0797
CI	0.219	0.0109*	0.216	0.0121*	− 0.186	0.0306*	0.229	0.0078**
CTA	− 0.445	< 0.0001	− 0.203	0.0181*	− 0.256	0.0028*	− 0.132	0.127

PFT, pulmonary function test; mPAP, mean pulmonary arterial pressure; PVR, pulmonary vascular resistance; CO, cardiac output; CI, cardiac index; CTA, CTA obstruction score; FEV_1.0, forced expiratory volume in 1 second; FVC, forced vital capacity; MMF, maximal mid‒expiratory flow; \({\dot{\text{V}}}\)50 and \({\dot{\text{V}}}\)25: flow at 50,and 25% of vital capacity
^*p < 0.05; **p < 0.01

ISSN: 1471-2466