Fig. 2

Gene distributions in mitochondrial genome of HAPE and non-HAPE groups. a Mutation densities (mutation number in a region/region bp length) in coding regions and non-coding regions of HAPE or non-HAPE group. b Number and proportion of frameshift variants, missense variants, stop gained, stop lost, synonymous variants and upstream gene variants. c Mutation rates in HAPE or on-HAPE individuals. P-value was obtained in t-test; *, P-value < 0.05; **, P-value < 0.01