Table 1 Demographic and clinical data stratified according to the three CT patterns (peripheral, multifocal, and diffuse)
Total (n = 69) | Peripheral pattern (n = 29) | Multifocal pattern (n = 28) | Diffuse pattern (n = 12) | p value | |
|---|---|---|---|---|---|
Characteristics | |||||
Male sex (%) | 21 (30%) | 11 (38%) | 7 (25%) | 3 (25%) | 0.52 |
Age (years) | 57.8 (47–72) | 55.2 (42–69) | 58.9 (49–72.5) | 61.8 (44–75) | 0.43 |
Hemodynamic parameters | |||||
Pulse rate (per min) | 87.17 (80–96) | 87.11 (80–98) | 86.12 (77–94) | 89.83 (83.5–100.5) | 0.75 |
Systolic BP (mmHg) | 122.82 (113–130) | 120.11 (112–130) | 127.72 (119–134) | 118.01 (107–129) | 0.06 |
Diastolic BP (mmHg) | 76.71 (68–86) | 73.61 (66–82) | 80.52 (70–90) | 75.13 (62–86.5) | 0.16 |
Body temperature (°C) | 37.5 (36.9–38) | 37.5 (36.8–37.8) | 37.7 (37.2–38.25) | 37.1 (36.45–37.6) | 0.04 |
Respiratory characteristics | |||||
Respiratory rate (breaths per min) | 20.71 (16–24) | 18.91 (16–20) | 22.12 (16–27.5) | 21.83 (18–24.5) | 0.10 |
SpO2 (%) | 95.59 (95–97) | 95.9 (95–98) | 96.1 (95–97.5) | 93.8 (91.5–96.5) | 0.08 |
PaO2/FiO2 ratio | 230.71(134.4-270.8) | 270.72(198.6-294.1) | 227.92(141.8-290.1) | 202.01(103-255) | 0.19 |
PaCO2 (mmHg) | 35.51(33.7-37.1) | 34.82(33.7-35.4) | 35.53(33.7-37.1) | 36.11(33.7-37.1) | 0.81 |
Biomarkers | |||||
WBC (×1000) (/μL) | 5.97 (4–7.1) | 5.81 (3.4–7.5) | 5.62 (3.8–6.55) | 7.31 (5.6–8.7) | 0.10 |
Lymphocyte count (/μL) | 889.95 (598–1190) | 1210.11 (852.6–1602) | 1003.43 (560.5–978.8) | 672.42 (328–1190) | 0.01 |
Neutrophil count (/μL) | 3859.45 (2252–4902.8) | 3478.31 (1788.4–4650.5) | 3597.91 (2532.7–4438.2) | 5842.24 (3062.7–7526.4) | 0.02 |
CRP (mg/dL) | 7.82 (1.43–11.92) | 5.83 (0.47–9.87) | 7.59 (1.905–11.71) | 13.32 (9.41–17.76) | 0.01 |
LDH (IU/L) | 320.15 (213–388) | 247.60 (184–302) | 314.83 (233.5–396.5) | 511.91 (358–629) | <0.01 |
KL6 (U/mL) | 408.28 (214–526.5) | 244.61 (190–234) | 293.41 (206–352) | 813.90 (473.5–1094.5) | <0.01 |
Platelet (×103/μL) | 192.59 (158–229) | 191.70 (149–242) | 187.82 (160–217.5) | 207 (146–229) | 0.66 |
D-dimer (μg/mL) | 4.18 (0.6–1.8) | 1.50 (0–1.6) | 0.99 (0–1.1) | 16.8 (1.5–25.9) | <0.01 |
Therapeutic agents | |||||
Steroid | 48 (69.57%) | 15 (52%) | 12 (43%) | 12 (100%) | 0.01 |
Heparin | 48 (69.57%) | 17 (59%) | 22 (79%) | 9 (75%) | 0.24 |
Favipiravir | 14 (20.29%) | 2 (7%) | 7 (25%) | 5 (42%) | 0.03 |
Severity scores | |||||
APACHE-II score | 16.78 (13–19) | 15 (11.5–18) | 16.3 (13–19) | 19.3 (15.5–23) | 0.37 |
SOFA score | 5.48 (3–7) | 4.5 (3–5.5) | 5.1 (3–6) | 7 (5–9) | 0.17 |