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Table 4 Details of infections during follow-up

From: Pulmonary involvement of ANCA-associated vasculitis in adult Chinese patients

 

Alveolar hemorrhage (n = 47)

Interstitial lung disease (n = 204)

Pulmonary granuloma (n = 54)

Airway involvement (n = 61)

Infectious patients, no. (%)

34 (72.3)

105 (51.5)

43 (79.7)

55 (90.2)a

First in-patient infection time, median (IQR) (weeks)

2 (2–9)

3 (2–17)

3 (3–13)

3 (2–9)

Infectious episodes, no. (%)

53

147

60

87

Infection pathogens, no. (%)

    

Bacteria

48/53 (90.6)

138/147 (93.8)

54/60 (90.0)

82/87 (94.3)

Fungus

20/53 (37.7)

38/147 (25.9)

15/60 (25.0)

20/87 (23.0)

 Pneumocystis jirovecii

0

8/147 (5.4)

3/60 (5.0)

3/87 (3.4)

 Aspergillus

3/53 (5.7)

6/147 (4.1)

6/60 (6.7)

3/87 (3.4)

 Candida

12/53 (22.6)

24/147 (16.3)

8/60 (13.3)

16/87 (18.4)

Viral

6/53 (11.3)

17/147 (11.6)

6/60 (10.0)

4/87 (4.6)

 CMV

2/53 (3.8)

6/147 (4.1)

6/60 (10.0)

1/87 (1.1)

 EBV

1/53 (1.9)

4/147 (2.7)

4/60 (6.7)

0

 Influenza virus

0

2/147 (1.4)

0

1/87 (1.1)

Locations of infection, no. (%)

    

Pulmonary

50/53 (94.3)

135/147 (91.8)

57/60 (95.0)

85/87 (97.7)

Genitourinary

1/53 (1.9)

17/147 (11.7)

2/60 (3.3)

7/87 (8.0)

Gastrointestinal

4/53 (7.5)

5/147 (3.4)

2/60 (3.3)

2/87 (2.3)

Catheter-associated

1/53 (1.9)

4/147 (2.7)

1/60 (1.7)

2/87 (2.3)

Sepsis

1/53 (1.9)

8/147 (5.4)

2/60 (3.3)

0

  1. AH Alveolar hemorrhage, AI Airway involvement, CMV cytomegalovirus, EBV Epstein-Barr virus, ILD interstitial lung disease, PG pulmonary granuloma
  2. p < 0.05: aILD vs. AI