Fig. 3

Flow cytometer data of mycobacteria EVs induced THP-1 monocytes cell death. THP-1 monocyte cells treated with mycobacteria EVs (10 µg/ml, 5 µg/ml, 2.5 µg/ml and 1.2 µg/ml), unstain cell, LPS, and healthy subjects. In most mycobacteria species, THP-1 monocytes cell death was increased by enhancing mycobacteria EVs multiplicities. P -value < 0.05 was considered