Table 1 Baseline demographics and comparison of demographics according to genotypes
From: Association between plasma sRAGE and emphysema according to the genotypes of AGER gene
|  | Total N = 436 | CC* n = 290 | TC + TT* n = 146 | P |
|---|---|---|---|---|
Age, years | 72.3 ± 7.1 | 72.4 ± 7.1 | 72.2 ± 7.2 | 0.710 |
Sex, male, n (%) | 316 (72.5) | 218 (75.2) | 98 (67.1) | 0.075 |
Emphysema index | 5.6 ± 6.3 | 6.5 ± 0.3 | 4.7 ± 0.5 | 0.002 |
Presence of emphysema | Â | Â | Â | 0.020 |
 Emphysema (−) | 287 (65.8) | 180 (62.1) | 107 (73.3) |  |
 Emphysema (+) | 149 (34.2) | 110 (37.9) | 39 (26.7) |  |
COPD, n (%) | Â | Â | Â | 0.040 |
 Non-COPD | 156 (35.8) | 93 (32.0) | 63 (43.2) |  |
 GOLD Stage 1 | 20 (4.6) | 12 (4.1) | 8 (5.5) |  |
 GOLD Stage 2 | 143 (32.8) | 92 (31.7) | 51 (34.9) |  |
 GOLD Stage 3 | 118 (27.0) | 90 (31.0) | 28 (18.2) |  |
Smoking status, n (%) | Â | Â | Â | 0.046 |
 Current | 96 (22.1) | 72 (24.9) | 24 (16.5) |  |
 Former | 180 (41.5) | 122 (42.2) | 58 (40.0) |  |
 Never | 158 (36.4) | 95 (32.9) | 63 (43.5) |  |
Smoking, Pack-years | 17.1 ± 22.8 | 18.1 ± 22.4 | 15.2 ± 23.6 | 0.223 |
Education | Â | Â | Â | 0.304 |
 < Elementary school | 132 (31.1) | 90 (31.9) | 42 (29.4) |  |
 Elementary school | 164 (38.6) | 101 (35.8) | 63 (44.0) |  |
 Middle school | 63 (14.8) | 38 (13.5) | 25 (17.5) |  |
 ≥ High school | 66 (15.5) | 53 (18.8) | 13 (9.1) |  |
sRAGE, pg/mL | 666.7 ± 338.8 | 720.9 ± 341.4 | 558.9 ± 307.5 |  < 0.001 |
Log sRAGE | 6.4 ± 0.4 | 6.4 ± 0.4 | 6.2 ± 0.5 |  < 0.001 |