Clinical features and long-term prognosis of acute fibrinous and organizing pneumonia histologically confirmed by surgical lung biopsy

Table 5 Comparisons between the survivor and non-survivor groups

	Survivor group (N = 7)	Non-survivor group (N = 8)	p-value
Demographics
Age, years	52.0 (40–78)	56.0 (33–77)	0.867
Sex, male	5 (71.4)	5 (62.5)	1.000
Never smoker	3 (42.9)	4/6 (57.1)	0.592
BMI, kg/m²	21.6 (18.3–27.7)	22.9 (20.9–24.8)	0.189
Immunocompromised state	3 (42.9)	1 (12.5)	0.282
Presentations and vital signs
Time from symptom onset to diagnosis	16 (6–26)	23 (7–62)	0.189
Presence of fever	5 (71.4)	8 (100)	0.200
SpO₂, %	91 (68–98)	90 (77–95)	0.535
PaO₂, mmHg	59.8 (47.8–72.2)	46.5 (40.6–65.7)	0.343
Laboratory findings
WBC, × 10³/μL	8.40 (4.30–12.30)	7.31 (0.96–16.40)	1.000
CRP, mg/dL	10.50 (0.30–24.60)	9.34 (1.10–28.30)	0.779
Procalcitonin, ng/mL	0.19 (0.07–0.90)	0.52 (0.05–1.69)	0.445
BAL fluid cell analysis*
Neutrophil dominant pattern	4/6 (66.7%)	3/6 (50.0%)	1.000
Radiologic findings
GGO/consolidation dominant type	3 (42.9%)	6 (75.0%)	0.386
Nodule dominant type	2 (28.6%)	2 (25.0%)
Fibrosis dominant type	2 (28.6%)	0 (0.0%)

Data are presented as n (%) or median(range)
p-value: Statistical significance test was done by Mann–Whitney U-test or Fisher’s exact test
^*Bronchoalveolar lavage (BAL) was done in 13 patients. One sample had few nucleated cells, so BAL fluid cell analysis were available in six out of seven survivors and six out of eight non-survivors

ISSN: 1471-2466