Bacterial and viral coinfection in idiopathic pulmonary fibrosis patients: the prevalence and possible role in disease progression

Table 3 Comparison of disease status, survival time and death occurrence between non-infected, bacterial-, viral- and co-infected IPF patients, respectively

Characteristics	Non-infected Group 1 (n = 8)	Bacterial Infection Group 2 (n = 7)	Viral Infection Group 3 (n = 12)	Coinfection Group 4 (n = 40)	p*	p⁺	p^$
Disease status⁻ (acute vs. stable)	0	1 (14.3)	1(8.3)	22 (55)	0.675	0.930	< 0.001
Death status⁻ (death vs. survive)	0	2 (28.5)	0	15 (37.5)	0.40	0.622	0.043
Survival time⁺ (months-to-death)	42.5 ± 6.55	38.5 ± 7.02	34.4 ± 2.83	32.9 ± 9.12	0.426	0.193	0.026

Disease- and death-status are indicated as “n” (%). Survival time is indicated as median ± IQR
IPF uninfected patients are considered as the reference group (Group 1). Bold values indicated as statistically significant at p < 0.05 level. Follow up period is 60 months
^*Comparison between group 2 versus group 1
⁺Comparison between group 3 versus group 1
^$Comparison between group 4 versus group 1

ISSN: 1471-2466