|
Variables
|
Total (n = 51)
|
OSA (n = 17)
|
Non-OSA (n = 34)
|
p Value
|
|---|
|
Age (years)
|
37 (33–39)
|
38 (35–40)
|
35 (32–39)
|
0.120
|
|
Gestational age (weeks) at plasma sampling
|
36 (34–37)
|
36 (34–36.5)
|
36 (34.75–38)
|
0.551
|
|
BMI before pregnancy (kg/m2)
|
26.7 (23.3–30.1)
|
29.2 (24.9–32.4)
|
25.76 (23.2–29.1)
|
0.15
|
|
Obese before pregnancy n (%)
|
13 (25.5)
|
6 (35.3)
|
7 (20.6)
|
0.256
|
|
First pregnancy n (%)
|
26 (52)
|
8 (50)
|
18 (52.9)
|
0.846
|
|
Pre-gestational smoker n (%)
|
|
No
|
27 (52.9)
|
7 (41.2)
|
20 (58.8)
|
0.393
|
|
Yes
|
15 (29.4)
|
7 (41.2)
|
8 (23.5)
|
|
Former smoker
|
9 (17.6)
|
3 (17.6)
|
6 (17.6)
|
|
Neck circumference (cm)
|
35.4 ± 3
|
35.1 ± 3.6
|
35.5 ± 2.8
|
0.634
|
|
Waist (cm)
|
110.2 ± 9.4
|
111 ± 11.4
|
109.8 ± 8.4
|
0.689
|
|
Hip circumference (cm)
|
115.7 ± 13.4
|
127.8 ± 18.3
|
112.1 ± 9.4
|
0.008
|
|
Glucose (mg/dL)
|
76.8 ± 8.9
|
74.5 ± 6.7
|
78 ± 9.6
|
0.186
|
|
Insulin (µUI/mL)†
|
11.8 (8.9–16.9)
|
18.2 (13.4–25.5)
|
13.4 (11.5–13.9)
|
0.137
|
|
HOMA-IR†
|
2.6 (1.7–3.2)
|
2.7 (1.8–4.9)
|
2.6 (1.2–2.8)
|
0.22
|
|
QUICKI†
|
0.33 (0.32–0.35)
|
0.33 (0.30–0.35)
|
0.33 (0.33–0.37)
|
0.202
|
|
Total cholesterol (mg/dL)
|
259 ± 57
|
258 ± 65
|
259 ± 54
|
0.952
|
|
Triglycerides (mg/dL)
|
221 (162–293)
|
216 (159–299)
|
232 (161–293)
|
0.865
|
|
HDL (mg/dL)
|
66 (58–75)
|
70 (60–82.5)
|
61 (50.5–72.5)
|
0.029
|
|
LDL (mg/dL)
|
144.9 ± 42.9
|
137.7 ± 35.3
|
148.5 ± 46
|
0.415
|
|
ALT (U/L)
|
16 (13–21)
|
17 (13.5–24)
|
15.5 (12–19.5)
|
0.275
|
|
GGT (U/L)
|
11 (7–16)
|
10 (7–15.5)
|
11 (7.8–16.5)
|
0.574
|
|
Hemoglobin (g/dL)
|
12.4 ± 0.14
|
12.8 ± 0.89
|
12.1 ± 1.04
|
0.032
|
|
Leucocytes (103/uL)
|
8.5 ± 2.06
|
8.79 ± 2.18
|
8.36 ± 2.02
|
0.496
|
|
Platelets (103/uL)
|
213 ± 8
|
195 ± 47
|
222 ± 60
|
0.112
|
|
Systolic BP (mmHg)
|
109 ± 12
|
111 ± 13
|
109 ± 12
|
0.990
|
|
Diastolic BP (mmHg)
|
68 ± 10
|
71 ± 11
|
66 ± 9
|
0.098
|
- Bold indicates statistically significant differences between the groups
- Descriptive analysis and comparison between groups. Continuous variables in mean ± SD if they follow normal distribution or in median (IQR) if they follow a non-parametric distribution. For categorical variables n (%). †Limited to noninsulin users (n = 30). Abbreviations: BMI body mass index, GDM gestational diabetes mellitus, HOMA-IR homeostasis model assessment of insulin resistance, HDL high-density lipoprotein, LDL low-density lipoprotein, ALT alanine aminotransferase, GGT gamma glutamyl-transpeptidase, BP blood pressure, g grams, kg kilograms, mg milligrams, m meter, cm centimetre, dL deciliter, U units, L liter, uL microliter, mmHg millimeter of mercury
