A comparative analysis of lung function and spirometry parameters in genotype-controlled natives living at low and high altitude

Table 2 Measured spirometric values between low and high altitude locations

Indicator	Sex	Low altitude	High altitude	Mean differences	Sig.
FVC ( L)	Women	2.6187	2.939	− 0.3203	0.789
	Men	3.5362	3.957	− 0.4208	0.720
FEV₁ (L)	Women	2.5541	2.7251	− 0.171	0.794
	Men	3.3505	3.602	− 0.2515	0.396
FEV₁/FVC ratio	Women	95.4385	92.761	2.6775	0.354
	Men	94.927	91.3533	3.5737	0.391
FEF25–75%	Women	3.9028	3.9478	− 0.045	0.781
	Men	4.7384	4.5457	0.1927	0.017
FEF25–75%—85%	Women	1.8954	1.7346	0.1608	0.536
	Men	2.4084	1.862	0.5464	0.008
PEF L/s	Women	5.6669	5.8726	− 0.2057	0.655
	Men	7.8292	7.8143	0.0149	0.906

Bold indicates a p-value less than < 0.05 is statistically significant
FVC (forced vital capacity), forced expiratory volume in 1 s (FEV1) ml, forced vital capacity (L), forced expiratory volume in 1 s (FEV1) (L), the FEV1/FVC ratio, also called Tiffeneau–Pinelli index) %, forced expiratory flow at 25–75% of forced vital capacity (FVC) (FEF25–75%) (L/s), forced expiratory flow at 25–75% of forced vital capacity (FVC) (FEF25–75%—85%) L/s, peak expiratory flow (L/s), body mass index (BMI) (kg/m²)

ISSN: 1471-2466