Table3 Univariate analyses of biomarkers for OS and PFS

Sex

Male

2.44

1.59–3.75

 < 0.001

2.26

1.51–3.40

 < 0.001

Age

1.01

0.99–1.03

0.241

1.01

0.99–1.03

0.257

Smoking

Yes

1.69

1.16–2.46

0.007

1.53

1.07–2.20

0.021

Pathology

Adeno

Another

1.73

0.85–3.51

0.128

1.7

0.87–3.32

0.122

SCLC

2.86

1.49–5.47

0.002

2.53

1.33–4.81

0.005

Squama

1.96

1.29–3.00

0.002

1.82

1.21–2.75

0.004

Size

1.01

0.99–1.02

0.327

1.01

1.00–1.02

0.262

PIS

Yes

1.78

1.20–2.64

0.004

1.96

1.35–2.85

 < 0.001

TNM

II

1.25

0.86–1.83

0.238

1.32

0.92–1.89

0.133

BMI

0.97

0.92–1.03

0.369

0.98

0.93–1.04

0.527

MLR

Low

0.39

0.27–0.57

 < 0.001

0.43

0.30–0.61

 < 0.001

NLR

Low

0.46

0.31–0.70

 < 0.001

0.49

0.33–0.72

 < 0.001

PLR

Low

0.57

0.39–0.83

0.004

0.64

0.44–0.91

0.014

D-Dimer

Low

0.4

0.24–0.67

 < 0.001

0.57

0.37–0.89

0.013

ECGO PS

0–1

0.26

0.18–0.39

 < 0.001

0.21

0.14–0.31

 < 0.001