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Table 1 Clinical and body composition characteristic in sarcopenia subjects

From: Association between body composition, sarcopenia and pulmonary function in chronic obstructive pulmonary disease

 

Total population n = 185

Sarcopenia n = 78

No sarcopenia n = 107

p-value

Age, years

72.20 ± 8.39

74.56 ± 7.60

70.48 ± 8.55

0.001

Male, n (%)

102 (55.14)

45 (57.69)

57 (53.27)

0.550

Diabetes, n (%)

44 (23.78)

17 (21.79)

27 (25.23)

0.587

Hypertension, n (%)

93 (50.27)

38 (48.72)

55 (51.40)

0.718

Obesity, n (%)

54(29.19)

6 (7.69)

48 (44.86)

 < 0.001

Heart failure, n (%)

72 (51.80)

34 (58.62)

38 (46.91)

0.173

FEV1, (%)

55.64 ± 22.64

53.30 ± 24.87

57.34 ± 20.82

0.230

FEV1, (L)

1.22 ± 0.58

1.09 ± 0.56

1.31 ± 0.57

0.009

FVC, (%)

74.92 ± 19.40

73.15 ± 21.06

76.21 ± 18.08

0.290

FVC (L)

2.29 ± 0.81

2.13 ± 0.78

2.41 ± 0.81

0.020

FEV1/FVC

0.53 ± 0.13

0.50 ± 0.15

0.54 ± 0.12

0.081

GOLD stage, n (%)

    

 1–2

105 (56.76)

43 (55.13)

62 (57.94)

 

 3–4

80 (43.24)

35 (44.87)

45 (42.06)

0.703

 CAT score

12 [7–18]

12 [9–20]

11 [6–16]

0.080

Group, n (%)

    

 A–B

94 (53.41)

35 (47.95)

59 (57.28)

0.221

 C–D

82 (46.59)

38 (52.05)

44 (42.72)

Hospitalization previous year, n (%)

81 (46.82)

39 (54.17)

42 (41.58)

0.102

Tobacco index, pack-year

40 [25–60]

40 [20–58]

43 [30–61.5]

0.164

Biomass index, h/yr

213 [77.5–360]

240 [80–385]

180 [51–360]

0.584

Inhaled bronchodilators, n (%)

144 (78.26)

64 (82.05)

80 (75.47)

0.285

Inhaled corticosteroids, n (%)

117 (66.30)

52 (66.67)

70 (66.04)

0.929

Height, cm2

158.00 ± 11.39

156.31 ± 12.35

159.23 ± 10.52

0.085

Body Mass Index, kg/m2

27.26 ± 5.70

24.05 ± 4.50

29.61 ± 5.34

 < 0.001

Fat Mass, kg

30.39 ± 10.03

27.51 ± 8.22

32.44 ± 10.71

 < 0.001

Fat Free Mass, kg

37.79 ± 12.05

30.92 ± 8.91

42.70 ± 11.63

 < 0.001

Handgrip strength, kg

23.72 ± 8.47

20.37 ± 7.76

26.22 ± 8.15

 < 0.001

Middle-upper arm circumference, cm

28.22 ± 4.25

25.92 ± 3.84

29.93 ± 3.71

 < 0.001

SMMI, kg/m2

8.31 ± 1.85

7.43 ± 1.44

8.94 ± 1.86

 < 0.001

ASMMI, kg/m2

6.79 ± 1.14

6.03 ± 0.74

7.35 ± 1.07

 < 0.001

Abdominal obesity, n (%)

140 (76.92)

45 (58.44)

95 (90.48)

 < 0.001

Phase angle, °

4.99 ± 0.88

4.57 ± 0.54

5.30 ± 0.95

 < 0.001

Exercise tolerance, m

324.34 ± 131.97

267.24 ± 128.12

388.58 ± 104.88

 < 0.001

  1. FEV1, Forced Expiratory Volume in the first second; FVC Forced Vital Capacity; GOLD stage Global Initiative for Chronic Obstructive Lung Disease stage; CAT COPD Assessment Test; SMMI Skeletal muscle mass index; ASMMI Appendicular Skeletal muscle mass index
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BMC Pulmonary Medicine

ISSN: 1471-2466

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