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Table 3 Predictors of RDW improvement after HMV initiation

From: Exploring red cell distribution width as a biomarker for treatment efficacy in home mechanical ventilation

Variable

Univariate

OR (95% CI)

Walds Chi2

p-value

Multivariate

OR (95% CI)

Walds Chi2

p-value

HMV duration (months)

1.51 (1.34–1.72)

p < 0.001

1.65 (1.42–1.91)

p < 0.001

Indication for HMV

 RCWD

30.00 (2.22–405.98)

p = 0.011

66.86 (3.63–1232.65)

p = 0.005

 OHS

9.84 (1.22–79.18)

p = 0.032

13.04 (1.35–132.73)

p = 0.027

  1. Logistic regression was used to identify variables closely related to improvement in RDW values (defined as clinically relevant improvement of 0.5% from baseline) including data from each study time point (n = 262). After univariate analysis of possible predictors (age, sex, haemoglobin value, HMV duration, HMV indication, interface type, referral type, paO2, paCO2), all significant variables and previously cited possible prognostic factors (age, sex, haemoglobin value) of RDW were entered into multivariate logistic analysis
  2. OR odds ratio, CI confidence interval, HMV home mechanical ventilation, OHS obesity hypoventilation syndrome, RCDW restrictive chest wall disease